Effects of non-drug treatment on the parameters of carbohydrate metabolism in patients with non-alcoholic fatty liver disease and obesity
Journal Title: Сучасна гастроентерологія - Year 2018, Vol 0, Issue 3
Abstract
Objective — to determine the efficacy of the complex non-drug treatment (NDT) on the course of non-alcoholic fatty liver disease (NAFLD) in patients with the concomitant obesity and on the associated disorders of the carbohydrate metabolism, in particular insulin resistance. Materials and methods. The investigation involved 105 NAFLD patients (55 men and 50 women, the mean aged 45.0 [37.0; 52.5] years). Patients were randomized in the groups of active NDT: 27 NAFLD patients (group ІB) and 27 NAFLD patients with concomitant obesity (group ІIB), and comparison groups: 25 NAFLD patients (group ІА) и 26 NAFLD patients with concomitant obesity (group ІІА). Results. It has been established that independently from obesity, active NDT associated with the reduction of fasting glycemia (р < 0.05), insulin levels (р < 0.05) and insulin resistance index НОМА (р < 0.05). Conclusions. Active non-drug NAFLD treatment during 24 week promoted the positive dynamics of the disease clinical course, and improvement of associated carbohydrate metabolism disorders.
Authors and Affiliations
O. G. Kurinna, I. E. Kushnir, V. M. Chernova, N. I. Cherelyuk
Keywords
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- EP ID EP298615
- DOI 10.30978/MG-2018-3-42
- Views 118
- Downloads 0
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