Effects of Vitamin C on Lead Induced Developing Thymus in Mice: A review
Journal Title: Universal Journal of Environmental Research and Technology - Year 2011, Vol 1, Issue 2
Abstract
The present review deals with effects of vitamin C on lead intoxicated developing thymus in mice .In the world of environmental health and medicine, lead exposure remains one of the most important problems in terms of prevalence of exposure and public health impact. Previous research has shown that every level of lead exposure is dangerous to animals and humans. Thus lead toxicity continues to be a leading environmental issue. Little is known about the persistent Immunotoxic effect of Pb when administered during specific stages of embryonic development. A variety of toxic effects caused by lead exposure during gestation and lactation have been reported in human and animal studies. Our immune system is our most powerful weapon against disease. Fetal and early postnatal life represents critical periods in vertebrate immune system development. Disruption of such development by Immunotoxic chemical exposure has been widely described in experimental animal model. The available animal data suggest the potential immune function in humans exposed immunotoxicants during fetal and early postnatal life. Administration of vitamin C results in improvement in several components of human immune response. Vitamin C regulates the immune system because of its antioxidant properties and its role in collagen synthesis required for stabilization of epithelial barriers. It plays a role in phagocytic function and has an immunostimulatory effect on lymphocyte cells. Limited information is available regarding the possibility of inhibited postnatal immune capacity in humans as a result of pre and postnatal immunotoxicant exposure. To fulfill this lacuna an attempt has been taken to gather the significant information on deformities in immune system due to immunotoxicant exposure during pre and postnatal development.
Authors and Affiliations
Sharma R. and Kantwa S. M
Keywords
Related Articles
- EP ID EP31628
- DOI -
- Views 568
- Downloads 4
Evaluation of Tolerant plant species in Urban Environment: A case study from Hyderabad, India
For the evaluation of tolerant capacity of the plant species to air pollution, four physiological and bio-chemical parameters namely leaf Relative Water Content, Ascorbic acid, leaf Chlorophyll content and leaf extract...
Colour Intensity, Fastness and Antimicrobial Characteristics of Silk Fabric Dyed with Mahua Bark
A study was conducted to analyse the shades and colour fastness property of silk fabrics dyed with colour extracted from mahua bark at different concentrations of mordants. Four types of mordants, viz. CuSO4, Al2(SO4)3...
Study on Correlation between Southwest and Northeast Monsoon Rainfall over Tamil Nadu
In the present study 110 years (1900-2010) data is used for studying correlative effects between southwest (June-September) and northeast monsoon (October –December) rainfall over Tamil Nadu. For the period of differen...
A Short Review on Process and Applications of Reverse Osmosis
Reverse Osmosis (RO) is a membrane based process technology to purify water by separating the dissolved solids from feed stream resulting in permeate and reject stream for a wide range of applications in domestic as we...
Improvement of Reproductive Health by Detecting Iron-Deficiency-Anemia in Adolescent Girls of Rural Area
Anemia is a public health problem and the primary cause of it is dietary deficiency though sometimes genetic abnormalities of hemoglobin synthesis and parasitic infections are the added reasons. In the present investig...