EFFICACY AND SAFETY OF ORMELOXIFENE IN REGRESSION OF MASTALGIA ASSOCIATED WITH FIBROCYSTIC DISEASE OF BREAST.
Journal Title: IJSR-International Journal Of Scientific Research - Year 2017, Vol 6, Issue 8
Abstract
Background: Mastalgia and brocystic breast disease is common occurance in women of reproductive age group.. Ormeloxifene is a weak oestrogen receptor (ER) agonist, a strong ER antagonist (SERA) and therefore a selective ER modulator (SERM)used in the treatment of the disease. Aim of study was to see the efcacy and safety of Ormeloxifene in regression of mastalgia associated with brocystic breast disease. Material and method- This was prospective trial, conducted in NMCH ,Patna from November 2015 to March 2017.. Fifty women of age 20-40 year with mastalgia associated with brocyctic disease of breast with VAS score more than 2 were treated with Ormeloxifene 30mg once daily on alternate days for a period of 3 months . Follow up was done monthly for 3 month and then at 6 month with Visual Analogue Scale (VAS) for pain and for side effect. Results-Total 63 patients were enrolled in the study. 13 patients left during trial . 50 patients completed the trial.The mean age was 34 year. The mean pain level was continuously decreased over 5 visit (4.72to 0.84) at 24 week.15(30%)patients reported oligomenorrhoea. Conclusion: Ormeloxifene showed signicant efcacy and safety for the treatment of mastalgia in brocystic breast disease.
Authors and Affiliations
Dr . Aashita Shrivastava
Keywords
Related Articles
- EP ID EP511183
- DOI -
- Views 59
- Downloads 0
THE PREVALENCE OF LEPROSY AT PRIMARY HEALTH CARE KARANG TALIWANG IN MATARAM, INDONESIA
Background: Leprosy is a chronic infectious disease that caused by Mycobacterium leprae. It's still endemic especially in underdeveloped or developing countries. The prevalence has decreased since the introduction of MDT...
A STUDY ON FACTORS AFFECTING CUSTOMER'S CHOICE OF SHOPPING MALLS
Shopping malls draw the attention of both sellers and buyers and provide sufficient time to customers for making choices and recreational options in shopping. Meanwhile, stiff competition between malls and usual shopping...
Accessory nipples- Review of literature with a case report
Polythelia is one of the commonest presentation of accessory breast. ey are usually found along the milk line. Sometimes they harbor malignancy so need to be considered in discussion. In this article there is a case rep...
FOCUSED ABDOMINAL SONOGRAPHY IN TRAUMA (FAST) IN PATIENTS WITH BLUNT TRAUMA ABDOMEN IN RURAL AREA- A PROSPECTIVE STUDY
Background: Unrecognized blunt abdominal injuries are often causing of the preventable death. Clinical examination is frequently inaccurate and therefore, the reliable, accurate and repeatable bed-side diagnostic test sh...
AN INSTALLATION OF APHERESIS KIT PRIMING PROCEDURE HAD MET WITH AN ACCIDENT AND MANAGED PROPERLY.
I would like to illustrate the observational case report of therapeutic plasma phresis kit installation and priming of kit had met a fall out as consequence of leaked of normal saline. We would like to get notified, rega...