Efficacy and Safety of Sublingual Misoprostol for Cervical Priming Prior To First Trimester Suction Evacuation
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 4
Abstract
Objective To evaluate the role of sublingual misoprostol as a cervical priming agent in first trimester pregnancy termination by suction evacuation Material and Methods A prospective randomized study carried was conducted in Dr Baba SahebAmbedkar Hospital, Delhi over a period of two years. 80 womenbetween 6-12 weeks of gestational age, seeking termination of pregnancy were randomized into two groups. Women in group I received sublingual misoprostol two hours prior to suction evacuation. Women in group II did not receive any treatment. The Outcome measures of the study : cervical dilatation,blood loss, duration of procedure and side effects were comparatively evaluated. Result The mean cervical dilation was 8.1 mm in sublingual misoprostol group compared to 2.5 mm in control (p value< 0.001). Blood loss and operative time was also significantly less. Minor side effects like nausea, vomiting and pain observed with misoprostol were well tolerated.
Authors and Affiliations
Neeru Malik, Dolly Chawla, Mohini Soni, Madhu Minocha, Neeraj Sharma
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