Efficacy of dexamethasone in prevention of trismus in mandibular third molar surgery
Journal Title: Scholars Academic Journal of Pharmacy - Year 2016, Vol 5, Issue 9
Abstract
Abstract:Corticosteroids (dexamethasone and methylprednisolone) have been reported to control postoperative outcome when given preoperatively. The aim of study is to evaluate efficacy of dexamethasone in prevention of trismus in mandibular third molar surgery. In a randomized double-blind and clinical trial study, 54 patients referred to Department of Oral and MaxillofacialSurgery with age range of 18-26 years. In case group, 20mg oral dexamethasone 2 hours before and 2 hours after surgery was used and in control group, 20mg multivitamintablet 2 hours before and 2 hours after surgery was used. How and maximum mouth opening were checked for every patients before surgery, 2 hours and 48 hours after surgery. The mouth opening size was statistically significant after 2 hours and 48 hours in case group compared with control group that the mouth opening size was more in case group compared with control group. The results showed that oral dexamethasone reduced trismus of third molar surgery and probably lower dose of dexamethasone has faster efficacy on incisal opening after surgery. Keywords:Third molar surgery, dexamethasone, trismus.
Authors and Affiliations
Hamid Reza Mozaffari, Mohammad Ramezanian, Masoud Sadeghi, Roohollah Sharifi, Shabnam Sadeghilar
Keywords
Related Articles
- EP ID EP377803
- DOI -
- Views 86
- Downloads 0
Determination of the active chemical compounds in the stem bark of Vitex trifolia Linn
Abstract: Vitex trifolia Linn. is known as a plant with compounds having antioxidant and anticancer activity. The current repot was conducted to isolate the stem bark of this plant in ethanol fraction. Ethanol ex...
Pharmaceutical formulation and quality control for Guggil-100 tablet(Commiphoramukul)
Today’s World Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances are combined to a pure drug substance to produce a final medicinal product. Formulation studies involve de...
Stimulate the antimicrobial activityof TiO2 nanoparticles (NPs) using methanol extract of Citrulluscolocynthis
Abstract:Recently, great efforts have been made to develop nanomaterials with bioactive compounds to enhance the antimicrobial activity of the NPs to develop the microbial inactivation techniques.Four local bacterial str...
Anatomical and Phytochemical Evaluation of Sansevieria roxburghiana Schult. & Schult. F. (Rhizome).
In the present study, rhizome of Sansevieria roxburghiana Schult. & Schult. f. (Agavaceae),was evaluated for the preliminary phytochemicals and anatomical characteristics. Petroleum ether, chloroform, methanol and wa...
Enhancement of Dissolution Rate of Gliclazide by Liquisolid Technique
The purpose of the present research was to investigate the in vitro dissolution properties of poorly water soluble gliclazide by utilizing liquisolid technique. Avicel PH 102 and Neusilin were employed as carrier materia...