Efficacy of oral Isotretinoin in viral warts
Journal Title: Journal of the Indian Medical Association - Year 2018, Vol 116, Issue 11
Abstract
Viral warts are commonly seen in dermatology OPD involving all age groups. Available treatment modalities have their own limitation like unacceptable side effects or inadequate efficacy. The present study was conducted to assess the efficacy of oral isotretinoin in the management of viral warts. Male agricultural workers in their 2nd to 4th decade were the most commonly subgroup of patients. Verruca vulgaris was the most common clinical subtype seen in 52.77% of the cases. Out of all body sites, upper limbs were affected in 37.5% followed by lower limbs in 31.94% and face in 10.18%. After isotretinoin therapy, complete response was seen in 87.09% of verruca plana, 60.78% of palmoplantar warts, 57.17% of verruca vulgaris and 30% of genital warts. However, 17.64% of palmoplantar wart and 14.91% of verruca vulgaris did not show any response. The common adverse effects observed were Chelitis (78.70%) followed by xerosis (36.57%), hair loss (3.70%) and hypertriglyceridemia (3.24%).
Authors and Affiliations
Manjulata Dash, Soubhagya Ranjan Tripathy, Tanmay Padhi, Nikhil Ranjan Das
Keywords
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