Efficacy of unilateral biportal endoscopy versus unilateral endoscopiy in the treatment of lumbar degenerative diseases: a Meta-analysis

Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 5

Abstract

<b>Objective</b> Meta-analysis was used to compare the efficacy of unilateral biportal endoscopy (UBE) and unilateral endoscopy(UE) in the treatment of lumbar degenerative diseases (LDD), in order to provide a reference for clinical treatment selection. <b>Methods</b> By searching the literature on UBE or UE treatment of LDD in PubMed, Web of Science, Wanfang database, CNKI and other databases, with searching date from March 2019 to November 2023. The quality of the collected literature was evaluated and the relevant outcome data were extracted, then Meta-analysis was conducted. The outcome indicators included: operative time, intraoperative blood loss, postoperative hospital stay, complication rate, number of intraoperative fluoroscopies, modified MacNab grading scale, visual analogue scale (VAS) for low back pain or leg pain, and Oswestry disability index (ODI). <b>Results</b> Sixteen papers (including 2 randomized controlled studies, 14 non-randomized controlled studies) with a total of 1 398 patients (including 709 patients treated with UBE , 689 patients treated with UE) were finally enrolled. The results of the Meta-analysis:compared with UE, the number of intraoperative fluoroscopy was higher in UBE [MD=0.16,95%CI(0.05,0.26),P=0.004]; the VAS score of back and leg pain and ODI in the early postoperative period were better[MD=-0.20,95%CI(-0.34,-0.07),P=0.004; MD=-0.17,95%CI(-0.33,-0.01),P=0.03;MD=-0.72,95%CI(-1.36,-0.08),P=0.03]. Subgroup analysis: for LSS,the operation time of UBE was shorter than that of UE[MD=-10.28,95%CI(-16.74,-3.82),P<0.01;the VAS score of postoperative back pain was better[MD=-0.22,95%CI(-0.42,-0.01),P=0.04]. For LDH,the operation time of UBE was longer than that of UE[MD=14.45,95%CI(4.07,24.84),P<0.01]; intraoperative blood loss was higher[MD=29.40,95%CI(12.52,46.28),P<0.01];however, postoperative ODI was better[MD=-0.84,95%CI(-1.39,-0.29),P<0.01]. <b>Conclusion</b> The results demonstrate that for LSS, UBE has the potential to reduce operative time. While for LDH, UE still has the advantages of less trauma, shorter operative time, and less blood loss. and in addition, UBE may have the potential to alleviate early postoperative low back pain and leg pain.

Authors and Affiliations

DING Yi*, CHEN Hao, WANG Xuepeng, WANG Haibin, ZHU Liulong, BIAN Zhenyu, LI Maoqiang

Keywords

Related Articles

Research advances on the association of nicotinic acetylcholine receptor-related genes and their polymorphisms with lung cancer

Pulmonary embolism and deep venous thrombosis are collectively referred to as venous thromboembolism, while pulmonary embolism is generally caused by deep venous thrombosis, which has the characteristics of sudden and mo...

Diagnostic value of serum soluble suppression of tumorigenicity 2 in patients with heart failure in different types of heart diseases

Objective To observe the changes of soluble growth stimulation expression gene 2 (sST2) level in patients with heart failure in different types of heart diseases, and analyze the diagnostic value of sST2 in heart failur...

Early sublingual microcirculation changes in patients with septic shock at different altitudes

Objective To observe the changes of early sublingual microcirculation in patients with septic shock at different altitudes, and to provide reference for clinical treatment of patients with septic shock at high altitude....

Clinical efficacy of full-visualization single-channel endoscopic posterior lumbar interbody fusion

<b>Objective</b> To analyze the clinical efficacy of full-visualization single-channel endoscopic lumbar interbody fusion (PE-PLIF) in the treatment of lumbar degenerative diseases, and to explore the application skills...

Timing of blood purification therapy in acute pancreatitis with systemic inflammatory response syndrome

"<b>Objective</b> To explore the timing of blood purification (BP) therapy in patients with acute pancreatitis (AP) who develop systemic inflammatory response syndrome (SIRS). <b>Methods</b> A retrospective collection...

Download PDF file
  • EP ID EP736339
  • DOI 10.13429/j.cnki.cjcr.2024.05.019
  • Views 47
  • Downloads 0

How To Cite

DING Yi*, CHEN Hao, WANG Xuepeng, WANG Haibin, ZHU Liulong, BIAN Zhenyu, LI Maoqiang (2024). Efficacy of unilateral biportal endoscopy versus unilateral endoscopiy in the treatment of lumbar degenerative diseases: a Meta-analysis. Chinese Journal of Clinical Research, 37(5), -. https://europub.co.uk./articles/-A-736339