Ekspresja koreceptorów CD80 i CD86 na limfocytach B w przerosłych migdałkach gardłowych u dzieci chorych na wysiękowe zapalenie ucha środkowego
Journal Title: Otolaryngologia Polska - Year 2010, Vol 64, Issue 2
Abstract
Aim: The aim of this study was evaluation of the percentage and mean fluorescence intensity of lymphocytes B with expression CD80 and CD86 in hypertrophied adenoids in children with otitis media with effusion. Material and methods: Expression coreceptors CD80 and CD86 on lymphocytes B in adenoid tissue were estimated by flow cytometry method. 15 children with otitis media with effusion and 15 children with hypertrophied adenoid were tested. Results: This study showed significantly higher percentage of lymphocytes CD19+CD80+ in children with otitis media with effusion (OME 1,42% ± 0,91) than in comparative group with hypertrophied adenoids (AH 0,63% ± 0,21). The receptor CD86 didn’t show differences in expression on lymphocytes B between both examinated groups. Conclusion: Low expression of CD80 and CD86 indicates that local immunity response in hypertrophied adenods in children with otitis media with effusion is weakened. It can contribute to the otitis media with effusion.
Authors and Affiliations
Karol Ratomski, Beata Żelazowska-Rutkowska, Jolanta Wysocka, Bożena Skotnicka, Edwina Kasprzycka, Ilona Bauer
Keywords
Related Articles
- EP ID EP51916
- DOI -
- Views 90
- Downloads 0
Scientific report from the 27th Politzer Society Meeting, London 3-5.09.09
Ocena jakości głosu po usunięciu nowotworów T1 i T 2 głośni z jednoczesną rekonstrukcją fałdu głosowego uszypułowanym płatem z mięśnia mostkowo-tarczowego
Introduction: In recent years there has been an increasing number of cases of cancer, including cancer of the larynx. The choice of treatment should be primarily dictated by the complete elimination of cancer, but from t...
A proposal for the classification of chronic sialadenitis of the major salivary glands with current diagnostic and treatment schedule
SUMMARY Approximately 5% of patients visit the ENT doctors with major salivary gland complaints. Chronic sialadenitis is one of the major disorders that can cause salivary hypofunction and correct diagnosis and managemen...
Markery metaboliczne nowotworów głowy i szyi – aplikacje kliniczne i podłoże biochemiczne
The problem of diagnosis in the field of head and neck region is still valid. Specific diagnosis and precise estimation of the tumor’s size with the use of CT and MRI imaging is generally unsatisfactory. The Positron Emi...
Zaburzenia połykania po laryngektomii całkowitej