Embedded Ag NPs in Cysteine-Poly (acrylic acid) Hydrogel with Antibacterial Activity
Journal Title: Asian Journal of Nanoscience and Materials - Year 2019, Vol 2, Issue 1
Abstract
In this research,Ag NPs were loaded on cysteine modified poly(acrylic acid) (PAA) hydrogel. Obtainedcysteine-hydrogel (Chydrogel) having different functional groups could stabilize Ag NPs better than un-modified hydrogel due to the presence of disulfid bondings. First, obtained PAA hydrogel from radical polymerization was conjugated with cysteine-hydrochloride (Cys) through amidation reaction and then was used as a substrate and stabilization reagent for Ag ions. Ag ions were reduced on Chydrogel in the presence ofNaBH4 as reducing reagent. The resultant nanocomposite was well characterized by using UV–vis, FT-IR, XRD and SEM techniques. Furthermore, the resultant Ag NPs on the surface of Chydrogel showedhigh antibacterial behavior against Gram-negative E. coliand Gram-positive S. aureusdue to the high reaction of thiol-functions with the outer cell surface.
Authors and Affiliations
Soghra Fathalipour, Mahdiye Ghanbarizadeh
Keywords
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- EP ID EP580182
- DOI 10.26655/ajnanomat.2019.1.3
- Views 80
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