Endometriosis–what is New in Medical Management with Progesterones
Journal Title: Indian Journal of Obstetrics and Gynecology - Year 2018, Vol 6, Issue 1
Abstract
Endometriosis affects women in their reproductive life and is a chronic disease. It is an important causes of dysmenorrhea, chronic pelvic pain and infertility. Diagnostic and therapeutic challenge is faced by clinicians as the disease tends to come back. Management is usually directed at relieving the symptoms and improving the chances of fertility which is either medical or surgical or a combination of the two. Some women with endometriosis might be asymptomatic, most have chronic abdominal &/or pelvic pain. Research is directed to find out ideal medication for endometriosis, with good efficacy, minimal or least side effects, cost- effective, and cantargets the basic pathology of disease to cures it. However, such cure is yet to be found. Many drugs are used to treat endometriosis- NSAIDs, combined oral contraceptive agents, Progesterones (oral, injections and local as intra uterine device. Every drug has its side effects and safety profile. Progesterones are generally preferred in very young as well as older women who cannot take long term OCP due to estrogenic side effects or contraindication Dienogest, a newer progestogen is closer to the ideal agent. Its profile is discussed below along with comparison with other progestins which are already being used. Other potential progestins are also discussed providing a whole spectrum of drugs with different efficacy and profiles.
Authors and Affiliations
Pratibha Singh
Keywords
Related Articles
- EP ID EP549452
- DOI 10.21088/ijog.2321.1636.6118.14
- Views 110
- Downloads 0
Immediate Maternal and Neonatal Effects of Forceps and Vacuum - Assisted Deliveries
Introduction: In certain conditions when normal delivery cannot be allowed for various reasons, assisted vaginal delivery is the method of choice. Vaginal delivery being assisted by instruments can either be of vacuum ex...
Outcome of Carcinoma Cervix Uteri Patients of Older Than 60 Years versus Less Than 60 Year
Aims and Objectives: Elderly patients of carcinoma cervix uteri are increasing in number. Outcome of cervical cancer with relation to age is controversial. We conducted a retrospective analysis in treated patients of car...
Case Series on Peripartum Cardiomyopathy
Introduction: Peripartum cardiomyopathy is an idiopathic and reversible form of dilated cardiomyopathy. It is defined as systolic heart failure in the last month of pregnancy or within 5 months of delivery. With an unkno...
A Study on Menstruation and Socio-Cultural Factor during Menstruation among Medical Students, Valsad, Gujarat
Background: In girls adolescence has been recognized as a special period marked with the onset of menarche. Even though menstruation is a natural process, it is associated with misconceptions, malpractices and challenges...
Cell-free DNA Results in Low Risk Pregnancy Screenings for Aneuploidies
Introduction: Chromosomal aneuploidies are a common type of chromosomal defect that may impose heavy burdens on society and families. The most common chromosomal aneuploidies among the embryos are trisomies 21, 18, and 1...