Endotracheal N-acetylcysteine for Atelectasis in Neonatal Pneumonia

Journal Title: The Journal of Pediatric Research - Year 2019, Vol 6, Issue 4

Abstract

Although there is no gold standard therapy in the treatment of atelectasis in newborns, surfactant therapy, inhaled mucolytic agents, recombinant human deoxyribonuclease, positive pressure mechanical ventilation, postural changes and drainage can be used. However, N-acetylcysteine (NAC), via endo-bronchoscopy, is rarely used to break the disulfide bonds in the mucus. It is a cheap and readily available treatment to apply. Here, we present a newborn with neonatal pneumonia to whom we instilled NAC thorough an endotracheal tube to resolve right lung total atelectasis. The atelectasis responded to instillation quickly and successfully. We are presenting this case in order to suggest a novel effective treatment modality for already intubated newborns with atelectasis. This case also represents the first successful treatment case in the newborn period.

Authors and Affiliations

Mustafa Dilek, Halil İbrahim Atasoy, Seher Açar

Keywords

Related Articles

Prevalence of Febrile Seizures in School-Aged Children: A Community Based Survey in İzmir, Turkey

Aim: Febrile seizures (FS) are the most common seizures seen in childhood. Although they are usually benign and self-limiting, parents feel great fear and concern about them. The prevalence of FS varies in different part...

Risk Factors of Bloodstream Infections Caused by Carbapenem-resistant Gram-negative Pathogens in Pediatric Critical Care Settings

Aim: Infections and sepsis are the leading causes of death in non-cardiac intensive care units (ICUs) and account for 40 percent of all ICU expenditures. Data regarding bloodstream infections (BSIs) due to a carbapenem-r...

Evaluation of Children with Congenital Heart Disease Hospitalized with the Diagnosis of Lower Respiratory Tract Infection

Aim: Lower respiratory tract infections are an important reason for mortality and morbidity in children with congenital heart disease. This study aimed to evaluate 50 children who had congenital heart disease and were ho...

Retrospective Comparison of Moderate and Severe Diaphragmatic Eventration in Children: Efficiency of Radiological Classification

Aim: Diaphragmatic eventration (DE) is a congenital or acquired elevation of the hemi-diaphragm. The indications for surgery may be challenging because clinical symptoms do not always correlate with radiological severity...

Extended-focused Ultrasonography for Children with High-energy Trauma

Aim: Ultrasonography (USG) is an important tool used in the diagnosis of critical patients. The present study was carried out in order to detect intra-peritoneal free liquid in cases with high-energy trauma by using “ext...

Download PDF file
  • EP ID EP665879
  • DOI 10.4274/jpr.galenos.2019.57442
  • Views 110
  • Downloads 0

How To Cite

Mustafa Dilek, Halil İbrahim Atasoy, Seher Açar (2019). Endotracheal N-acetylcysteine for Atelectasis in Neonatal Pneumonia. The Journal of Pediatric Research, 6(4), 359-362. https://europub.co.uk./articles/-A-665879