Enzymatic Profile of Alkaline and Acid Phosphatase In Gcf of Patients with Chronic Periodontitis.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Objective: This Study Was Done To Evaluate The Level Of ALP And ACP As Potential Biochemical GCF Markers Among Chronic Periodontitis Patients. Materials And Methods: A Total Of 60 Subjects Were Selected For The Study. The Study Population Was Further Divided Into 3 Group (Group 1 – Clinically Healthy Periodontium, Group – 2 Gingivitis, Group – 3 Periodontitis )Based On Clinical Assessment Of Probing Depth , Bleeding On Probing And Radiographic Evaluation Of Bone Loss. GCF Samples Were Taken To Assess The Level Of Enzymes .Results: Obtained Results Were Shown Statistically Significant Increase In The Level Of ALP Activity In GCF From Patients With Gingivitis And Periodontitis In Relation To Control Group. There Was Positive Correlation Between The Activity Of Examined GCF Enzymes And Values Of The Gingival Index And Periodontal Disease Index. Conclusion: Based On These Results, It Can Be Assume That Activity Of These Enzymes In GCF May Be Used As Potent Biochemical Markers For Periodontal Destruction.
Authors and Affiliations
K. Hameedfathima 1 ,, V. S. Harish2 .
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