Epidemiologic Study of Ventilator Associated Pneumonia in Neonatal Intensive Care Unit
Journal Title: Vajira Medical Journal: Journal of Urban Medicine - Year 2022, Vol 66, Issue 1
Abstract
Objective: To determine the bacterial pathogens and susceptibility patterns causing ventilator associated pneumonia (VAP) in neonatal intensive care unit (NICU) Methods: Retrospective descriptive study, collected data from microbiology department and medical records of newborn diagnosed as VAP at Faculty of Medicine Vajira Hospital, Navamindradhiraj University since January 1, 2016 to October 31, 2020. Results: Forty four of specimens from sputum were diagnosed with VAP. The major pathogens were gram negative bacteria (93.2%) which included S. maltophilia (36.4%), P. aeruginosa (34.1%), A. baumannii (9.1%), Acinetobacter spp. (6.8%), E. coli, K. pneumoniae and Klebsiella spp. (2.3% each equally). A gram positive bacterium was S. aureus 6.8% which sensitive to methicillin 100% . All S. maltophilia isolates were sensitive to ceftazidime, ciprofloxacin, imipenem and piperacillin/tazobactam. A.baumannii isolates were 100% sensitive to colistin and tigecycline, 50% sensitive to amikacin, cefoperazone/sulbactam, ceftazidime, ciprofloxacin, gentamicin, imipenem, meropenem and piperacillin/tazobactam. P. aeruginosa isolates were 100% sensitive to amikacin, cefoperazone/sulbactam, gentamicin and piperacillin/ tazobactam, 92.9% sensitive to ceftazidime and meropenem, 88.9%, 86.7% and 85.7% were sensitive to ciprofloxacin, imipenem and colistin, respectively. E. coli was ESBL 100% that all susceptible to amikacin, ceftazidime, carbapenems and piperacillin/tazobactam. Conclusion: The bacterial pathogens causing VAP in NICU at Faculty of Medicine Vajira Hospital were S. maltophilia, P. aeruginosa, A. baumannii, Acinetobacter spp., E .coli. The empirical antibiotic of choice is piperacillin/tazobactam or ceftazidime or carbapenems. Combination with aminoglycosides or ciprofloxacin is crucial for severe case and cloxacillin for suspected S. aureus. In case of carbapenem resistant A. baumannii (CRAB) and not improve with other empirical antibiotics, consider tigecycline plus colistin.
Authors and Affiliations
Suphawe Wasuanankun Uraporn Phumisantiphong Taweewong Tantracheewathorn
Keywords
Related Articles
- EP ID EP723836
- DOI http://dx.doi.org/10.14456/vmj.2022.5
- Views 44
- Downloads 0
Clinical Outcomes of Patients with Heart failure at the Heart Failure Clinic, Sunpasitthiprasong Hospital
Objective: To study the clinical outcomes of heart failure (HF) patients at the HF clinic, Sunpasitthiprasong Hospital. Method: Descriptive study was applied. Purposive sampling was used to recruit 34 patients with HF....
Incidental Appendiceal Neuroendocrine Tumors (NETs): A Case Report and Review Of Literature
Incidental appendiceal neuroendocrine tumors (NETs) are rare and mostly asymptomatic or come with clinically suspected appendicitis. Although, there is a various review of literatures and consensus guidelines, there has...
Food Consumption Behaviors of Third-Year to Fifth-Year Medical Students at the Faculty of Medicine Vajira Hospital
Objective: To study the food consumption behaviors, attitudes towards food consumption and factors relating to food consumption behaviors of third-year to fifth-year medical students at the Faculty of Medicine Vajira Hos...
Resilience, Mental Health Impact and COVID-19 Related Mental Health Determinants among Medical Students during COVID-19 Epidemic
Objective: To study the level of resilience in medical students and how resilience is associated with mental health during COVID-19 epidemic. Method: This is a cross-sectional descriptive study. The participants are the...
Agreement of Prehospital Severity Assignment: Comparisons among 3 Different Patient Assessment Tools in Urban Emergency Medical Service
Introduction: Emergency Medical Services (EMS) in Thailand are considered as multi-tiered response system providing medical care regarding the degrees of emergency and severity prioritization. Thus, effective triage tool...