Epidemiological analysis of 22 patients with congenital bleeding diathesis hospitalized in the Department of Maxillofacial Surgery in Lublin, Poland, 2008–2013
Journal Title: Journal of Pre-Clinical and Clinical Research - Year 2016, Vol 10, Issue 1
Abstract
[b]Introduction. [/b]Haemophilia A and B are congenital bleeding disorders caused by coagulation factor VIII or IX deficiency. Haemophilia A and B occur in men, like all qualities dependent on genes linked to gender, whereas women are asymptomatic carriers of the gene. The most dangerous manifestations of severe haemophilia include spontaneous haemorrhages into the joints, muscles and body cavities, haematuria and potentially very dangerous intracranial haemorrhages are also quite frequent. The most common manifestations in the region of the maxillofacial skeleton and oral cavity are recurring bleedings from the nose and the gums after dental extractions, as well as extensive haemorrhages from wounds after surgical procedures. [b]Objective[/b]. The aim of the study was the analysis of epidemiologic case records of 22 patients affected by various types of haemophilia, admitted to Maxillofacial Surgery Department at Medical University in Lublin, Poland, during 2008–2013. [b]Results[/b]. The most numerous group constituted patients diagnosed with Haemophilia A, followed by patients with von Willebrand disease and Haemophilia B, aged 21–40 years. The main cause of hospital admission was the need to perform complex oral cavity sanation. The patients were treated with factor VIII or Factor IX, FEIBA or Heamate P, depending on the type and severity of bleeding diathesis.
Authors and Affiliations
Jolanta Wojciechowicz, Anna Gawęda, Patryk Kasprzak, Bożena Sokołowska, Tomasz Tomaszewski
Keywords
Related Articles
- EP ID EP79298
- DOI 10.5604/18982395.1208188
- Views 90
- Downloads 0
Trace elements as constituents of antioxidative proteins
The human body is under constant attack by free radicals (reactive oxygen species – ROS). Free radicals are highly reactive molecules generated by biochemical redox reactions which occur as a part of regular cell metabo...
Resting heart rate variability and plasma noradrenaline level as a measurement of autonomic nervous system activity in mature, aging rats
[b]Introduction and objective.[/b] Aging is a process that also affects the autonomic nervous system (ANS) making it less adaptable to environmental and intrinsic stimuli and affecting its ability to maintain body homeos...
Study on free amino acid concentrations in umbilical cord blood plasma of newborns from normoglycaemic and gestational diabetes-complicated pregnancies
[b]Introduction and objective. [/b]Gestational diabetes mellitus is a common disease among pregnant women. The aim of the study was to compare plasma concentrations of 24 amino acids in umbilical cord blood in newborns f...
Cervicofacial actinomycosis following jaw pathology – Case Reports
Cervicofacial actinomycosis is a specific, primarily chronic inflammatory process caused by Gram-positive anaerobic, microaerophilic Actinomyces bacteria. The infection usually results from the skin or mucosal lesions. T...
Paraneoplastic syndromes in daily clinical practice
Paraneoplastic syndromes consist of disorders that accompany benign and malignant tumours, but are not directly related to mass effects or invasion by the primary tumour or its metastases. The pathophysiology of mostly p...