Epidemiology of Histopathologically Diagnosed Mycoses: The Ibadan 37 Years Experience
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 10, Issue 3
Abstract
Background: Recent studies suggest that the occurrence of mycotic infections is increasing worldwide, due to predisposing factors such as immunosuppression from chemotherapy, surgery, HIV/AIDS and debilitating diseases, but there is paucity of information regarding fungal infections in our environment. Aim: This study aimed to characterise mycoses diagnosed histopathologically in the Department of Pathology, University College Hospital (UCH), Ibadan between 1970 and 2006. Methods: The surgical pathology and autopsy records of all mycoses diagnosed during the study period were retrieved and analysed. One hundred and eighty-six mycoses were recruited. Results: There was a progressive decline in the annual occurrence of mycoses from 19.7% to 1.1%. The cases comprised 121 males and 65 females, whose ages ranged from 6 weeks to 80 years, with 68.3% being less than 40 years of age. The mean age of the male patients (29.9±18.4 years) was not significantly different from that of the females (27.4±18.2 years), t = 0.867, df = 186, p = 0.387. The most common mycotic infections were African histoplasmosis (28%), aspergillosis (12.4%), mycetoma (9.7%), candidiasis (8.6%) and actinomycosis (7%). Systemic mycoses accounted for 62%, followed by subcutaneous mycoses (21%), cutaneous mycoses (11%) and superficial mycoses (6%). The most common sites involved were the skin (23.7%), upper and lower limbs (15.6%), nose (11.3%) and lungs (7%). Conclusion: The present study has demonstrated that fungal infections are common and account for significant morbidity and disease burden in our environment.
Authors and Affiliations
B. A. F. Ngwu, A. O. Oluwasola, F. E. Iyare, J. O. Ogunbiyi, E. E. Akang
Keywords
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- EP ID EP348195
- DOI 10.9734/BJMMR/2015/19301
- Views 53
- Downloads 0
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