Epilepsy among Cerebral Palsy Children: Clinical Predictors and Frequency
Journal Title: International Neuropsychiatric Disease Journal - Year 2016, Vol 6, Issue 2
Abstract
Introduction: Epilepsy is one of the most common neurological disorder in childhood. The risk of epilepsy is highest in children with brain abnormalities, such as cerebral palsy. There are a lot of studies showing that epilepsy varies from 12-19 percent in children with CP. Objective: The objective of this study is to determine the relationship between cerebral palsy (CP) and epilepsy and how to predict development of seizures among cerebral palsy children. Subject and Methods: A prospective study included 82 patients with cerebral palsy and history of seizure. Seizure were classified according to ILAE classification, an EEG and neuro-imaging were obtained in all cases. We analyzed the incidence of different types of epilepsy in relation to different subtypes of cerebral palsy. Other factors associated with epilepsy such as age of starting first attack, neonatal seizures and familial factors were also analyzed. Results: In our study the most common risk factors were perinatal factors 40 patients (48.8%): 16 of them had epilepsy. While the less common risk factors were postnatal factors 10 patients (12.2%): 6 of them had epilepsy. The incidence of epilepsy in our sample was significantly higher with very sever types of CP affecting 58.8% of very sever CP (P = 0.007). In contrary the mild type of CP was significantly associated with 3% only of the prevalence of epilepsy (P = 0.05). Abnormal CT brain findings were found in only 19 (39.6%) patients and there was no abnormality in CT brain in 29(60.4%) patients. High prevalence of epilepsy was associated with neonatal seizures and positive family history of epilepsy (p<0.005). Conclusions: Epilepsy among children with CP is common and the most common risk factors were perinatal factors. The predominant form of epilepsy was generalized. Brain CT imaging allowed definition of extent of associated brain damage and mostly significant frequency of abnormal findings were detected in epileptic CP children.
Authors and Affiliations
Osama Abdel Salam, Ahmed Esmael, Mohamed El-Sherif
Keywords
Related Articles
- EP ID EP241721
- DOI 10.9734/INDJ/2016/22785
- Views 117
- Downloads 0
Treatment of Catatonia Using Low Doses of Clozapine
Catatonia is a state of apparent unresponsiveness to external stimuli in a person who is apparently awake and which occurs in children, adolescents, and adults and is characterized by a variety of symptoms and signs of i...
Diffusion-weighted MR Imaging of the Brain: Correlation of Ischemic Lesion Patterns with ASCO Stroke Subtypes
Background: There are many etiologies for ischemic cerebral stroke. Previous studies have not shown whether specific ischemic lesion patterns on early brain diffusion-weighted imaging (DWI) are associated with specific i...
A Case of Polydipsia in a Psychiatric Patient
A 28 year old male student, with a long standing history of psychotic disorder, presented with excessive water intake and symptom exacerbation with associated confusion, vomiting and irrational talk, that has started a w...
Emotional Intelligence, Spiritual Intelligence, Self-esteem and Self Control of Substance Abuse
Background: This study aims to investigate the relationship between emotional intelligence, spiritual intelligence and self-esteem, and self-control on men with addiction in rehabilitation centers of Tehran. Methods: Thi...
Treatment of Primary Headaches in Paediatric Age: A Comprehensive Review
Primary headaches have a high prevalence in paediatric age and may pose a high strain on the quality of life of young patients. Adequate care involves a patient-by-patient approach, and this generally relies both on bio-...