Epilepsy among Cerebral Palsy Children: Clinical Predictors and Frequency
Journal Title: International Neuropsychiatric Disease Journal - Year 2016, Vol 6, Issue 2
Abstract
Introduction: Epilepsy is one of the most common neurological disorder in childhood. The risk of epilepsy is highest in children with brain abnormalities, such as cerebral palsy. There are a lot of studies showing that epilepsy varies from 12-19 percent in children with CP. Objective: The objective of this study is to determine the relationship between cerebral palsy (CP) and epilepsy and how to predict development of seizures among cerebral palsy children. Subject and Methods: A prospective study included 82 patients with cerebral palsy and history of seizure. Seizure were classified according to ILAE classification, an EEG and neuro-imaging were obtained in all cases. We analyzed the incidence of different types of epilepsy in relation to different subtypes of cerebral palsy. Other factors associated with epilepsy such as age of starting first attack, neonatal seizures and familial factors were also analyzed. Results: In our study the most common risk factors were perinatal factors 40 patients (48.8%): 16 of them had epilepsy. While the less common risk factors were postnatal factors 10 patients (12.2%): 6 of them had epilepsy. The incidence of epilepsy in our sample was significantly higher with very sever types of CP affecting 58.8% of very sever CP (P = 0.007). In contrary the mild type of CP was significantly associated with 3% only of the prevalence of epilepsy (P = 0.05). Abnormal CT brain findings were found in only 19 (39.6%) patients and there was no abnormality in CT brain in 29(60.4%) patients. High prevalence of epilepsy was associated with neonatal seizures and positive family history of epilepsy (p<0.005). Conclusions: Epilepsy among children with CP is common and the most common risk factors were perinatal factors. The predominant form of epilepsy was generalized. Brain CT imaging allowed definition of extent of associated brain damage and mostly significant frequency of abnormal findings were detected in epileptic CP children.
Authors and Affiliations
Osama Abdel Salam, Ahmed Esmael, Mohamed El-Sherif
Keywords
Related Articles
- EP ID EP241721
- DOI 10.9734/INDJ/2016/22785
- Views 108
- Downloads 0
Sensory Integration Capacity is Diminished in Obsessive Compulsive Disorder Patients with Poor Insight But Not in Patients with Intact Insight
Aims: The aim of the present study was to assess sensory integration ability of OCD patients with poor and good insight using a Haptic Test for adults. Study Design: Experimental design. Place and Duration of Study: Depa...
Epilepsy among Cerebral Palsy Children: Clinical Predictors and Frequency
Introduction: Epilepsy is one of the most common neurological disorder in childhood. The risk of epilepsy is highest in children with brain abnormalities, such as cerebral palsy. There are a lot of studies showing that e...
Preschoolers of Mothers with Affective and Anxiety Disorders Show Impairments in Cognitive Inhibition During a Chimeric Animal Stroop
Aims: To determine whether maternal affective and anxiety disorders are associated with cognitive inhibitory deficits in four-year-old children utilizing a chimeric animal stroop task, a childhood adaptation of the tradi...
Clinical Profile of Children with Cerebral Palsy in Jos, North-Central Nigeria
Aim: The aim of this study was to describe the clinical profile of children with cerebral palsy (CP) at Jos University Teaching Hospital (JUTH), Jos, North-Central Nigeria. Study Design: This was a case series study. Pla...
Psychological Assessment and Five Years Follow up of a Client under Vocational Guidance: A Case Study
This case study was carried out to undertake a psychological assessment and follow up of an undecided client who needed vocational guidance and counseling to make an appropriate and correct career choice. The case study...