Epinephrine as Epidural Adjuvant to Bupivacaine and Fentanyl in Elective Orthopedic Surgeries
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 5
Abstract
Epinephrine when used as an epidural adjuvant to thoracic epidural anesthesia was found to prolong the duration of anesthesia and also enhance the motor blockade. When it was used as adjuvant in labour analgesia it was found to have disadvantages of having denser motor block. The vasoconstriction and α2 agonism was the reason hypothesized to the above action of the epidural Epinephrine. Hence our study was designed to study the effects of Epinephrine in epidural anesthesia with Bupivacaine and Fentanyl in patients undergoing elective orthopedic surgeries in supine position. Study involved 40 patients, of whom 20 patients received 0.5% Bupivacaine with 1 µg/ml of Fentanyl and 5 µg/ml of Epinephrine and 20 of them, received 0.5% Bupivacaine with 1 µg/ml of Fentanyl. We compared the two groups for the onset of the sensory and motor block, degree of motor block, duration of analgesia and hemodynamics. From our study we could conclude that addition of Epinephrine at 5 µg/ml to 0.5% Bupivacaine and 1 µg/ml of Fentanyl resulted in enhancement of the onset of block, with higher degree of motor blockade. But the duration of analgesia was not enhanced by addition of Epinephrine. Keywords: Epinephrine, Bupivacaine, Fentanyl, Epidural anesthesia
Authors and Affiliations
Darshan M. S, Sri Devi S, Karthik A, Jeyakumar V, Nagasunitha C. H
Keywords
Related Articles
- EP ID EP374744
- DOI -
- Views 79
- Downloads 0
Susceptibility of Humans of The ABO Blood Groups to P. falciparum infection Among Patients Attending Ahmadu Bello University Clinic (Sickbay), Samaru-Zaria, Kaduna State, Nigeria.
Abstract: The effects of patients’ blood groups, age and sex on the prevalence of malaria in the Ahmadu Bello University Clinic (Sickbay), Samaru-Zaria, Kaduna State were investigated. A total of 178 (24.5%) of 728 patie...
Assessment of speed of post mortem alteration to skeletal microstructure
Abstract: The assessment of microstructural influence on post mortem changes usually depends over human skeletal system. Various works stated that post mortem alteration to skeletal material can be extensive, and can occ...
Meningitis among Children admitted to Benghazi Pediatrics Hospital during 2012
Meningitis is a severe and feared disease, caused by an infection of the fluid that surrounds the brain and spinal cord. It can be caused by bacteria, viruses, protozoa, fungi, and other agents. Many of the viruses and b...
Evaluation of pulmonary function tests among smokers and non-smokers
Abstract: Cigarettes kill an estimated 5 million people annually worldwide. The World Health Organization reported that tobacco smoking killed 100 million people worldwide in the 20th century and warned that it could kil...
A comparative study of hydralazine versus labetalol in the management of pregnancy induced hypertension (PIH).
Abstract: The objective of this study is to compare the efficacy as well as safety profile of Hydralazine and Labetalol in severe pregnancy induced hypertension. 100 women with severe pregnancy induced hypertension were...