Erythrophagocytosis in Bone Marrow: A Clue to Pyrexia of Unknown Origin
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2018, Vol 8, Issue 2
Abstract
Erythrophagocytosis in Bone Marrow: A Clue to Pyrexia of Unknown Origin Neha Garg, Surabhi Raina, Mrinalini Kotru, Meera Sikka Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India ABSTRACT Bone marrow (BM) is usually done to investigate the patients for Pyrexia of Unknown Origin (PUO). However, only 16.5 % of cases reveal any diagnostic information. Increasing incidence of atypical presentations is seen in typhoid. Careful examination of BM to pick up clues for diagnosis is important. We report a case of a 15 year old female who presented with fever associated with altered sensorium, gum bleeding and loose stools. Hematological findings revealed pancytopenia with macrocytic anemia with erythrophagocytosis in BM aspirates. A diagnosis of typhoid was made with a positive typhi dot IgM. The authors present this case to highlight the importance of simple BM findings of erythrophagocytosis and how awareness about this feature can point towards the right diagnosis in the midst of atypical clinical and hematological features. J Microbiol Infect Dis 2018; 8(2):73-75
Authors and Affiliations
Neha Garg, Surabhi Raina, Mrinalini Kotru, Meera Sikka
Keywords
Related Articles
- EP ID EP480572
- DOI 10.5799/jmid.434605
- Views 112
- Downloads 0
şitme kaybı: Nörobruselloz olabilir mi?
Brusella, insanlara çoğunlukla enfekte yiyeceklerin yenmesiyle veya enfekte hayvan ile doğrudan temas yoluyla geçen bir zoonozdur. Her organ sistemini tutabilir ve buna bağlı olarak çok çeşitli klinik bulgularla ort...
Identification of Ochrobactrum oryzae in Primary loodstream nfection in a ialysis Patient: Can it be an Emerging Pathogen
Ochrobactrum spp is a gram-negative bacillus currently considered an emerging and opportunistic infection, rare in humans, and generally associated with indwelling foreign bodies. We report a case of primary bloodstream...
Crimean-Congo hemorrhagic fever and pregnancy: Two cases
Crimean-Congo Hemorrhagic Fever (CCHF) is a viral zoonosis, transmitted to humans by either: the Hyalomma species of ticks; or by direct contact with body fluids or tissues of infected humans or domestic animals. CCHF c...
Class 1 Integron, Sulfonamide and Florfenicol Resistance Genes in Bacteria from Three Unsanitary Landfills, Ibadan, Nigeria
Objective: Municipal solid waste (MSW) landfills recently emerged as potential reservoirs of antibiotic resistance. However, little is known about the potentials of unsanitary landfill sites which are common in developin...
Burden of acute gastrointestinal infections in Ouagadougou, Burkina Faso
Objective: Gastrointestinal infections are one of the major health problems in developing countries. The present study aims to estimate the prevalence of gastrointestinal infections in Ouagadougou, the capital of Burkina...