Estimation of the Level of (25) Hydroxy Vitamin D in Elderly Patients with Chronic Obstructive Pulmonary Disease
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Introduction: Chronic obstructive pulmonary disease (COPD) is characterized by airflow obstruction that is not fully reversible. The airflow limitation is usually progressive and is associated with an abnormal inflammatory response of the lungs to noxious particles or gases. The airflow obstruction is due to a combination of airway and parenchymal damage.People over age 50 have an increased risk of vitamin D deficiency and the risk increases with ageIn elderly COPD, the risk of vitamin D deficiency is higher than expected and is linked with disease severity. Aim of the work:The aim of the present work is to measure the level of 25, hydroxy-vitamin D in elderly with and without chronic obstructive pulmonary disease (COPD). Methods:This study wasconducted on 60 subjects aged 60 years and above who were attending Al Noor specialistHospital in holly Makah and they were divided into two groups: Group I:30 patients with COPD.Group II:30 elderly non COPD subjects.All subjects were subjected to detailed history taking,clinical examination, and laboratory investigations. Serum (25) hydroxy vitamin D level was measured in (March, April 2013).Arterial blood gases when needed.GOLD grading. Geriatric depression scale "short form". Charleston scores for co-morbidities. Results:This study showed that.In group I; 18 patients (60%) had mild to moderate 25(OH)D deficiency and 12 patients (40%) had sever deficiency, while in group II; 27(90%) had normal level and 3(10%) had mild to moderate deficiency Also there was statistically significant negative correlation between 25(OH)D level and GOLD grading. Conclusion: 25(OH)D deficiency is highly prevalent in elderly COPD patients and it is correlated with the disease severity.
Authors and Affiliations
Salah F. Alsayed, Ahmed M. Baraka, Saber A. M. El- Sayed, Majed Hameed Madloul
Keywords
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- EP ID EP431033
- DOI 10.9790/0853-1801038690.
- Views 66
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