ESTIMATION OF VITAMIN D LEVELS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 7
Abstract
BACKGROUND Vitamin D deficiency and osteoporosis is a common extra pulmonary manifestation in COPD patients. Evidence suggests that the prevalence of osteoporosis in patients with COPD is high and potentially important with disease progression. AIM- The aim of this study was to estimate the serum Vitamin D levels in a well-defined cohort of patients with COPD and to correlate stages of COPD with Vitamin D level. MATERIAL AND METHODS It is a case control study, done over a period of 1 year in a tertiary care centre in North India. The study group was consisting of 60 male & female COPD patients diagnosed by spirometry and severity was determined according to GOLD classification criteria as well as age and sex matched 60 healthy controls. RESULTS Vitamin D level was found to be lower in cases as compared to controls and deficiency was more severe in higher stages of COPD (p<0.001). CONCLUSION Vitamin D deficiency correlated well with severity of COPD. Therefore, an early intervention with vitamin D supplementation might play a significant role in decreasing the comorbidity of COPD.
Authors and Affiliations
Kamlesh Kumar Gupta, Shyam Chand Chaudhary, Surendra Kumar Khunte, Kamal Kumar Sawlani, Arvind Kumar Mishra, Vivek Kumar, Virendra Atam, Satyendra Kumar Sonkar
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