ETHNOMEDICINAL, PHYTOCHEMICAL AND PHARMACOLOGICAL ASPECTS OF FLACOURTIA JANGOMAS: A REVIEW

Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2018, Vol 10, Issue 3

Abstract

Flacourtia jangomas (Lour.) Raeusch., a small tree of Willow family distributed throughout tropical regions of East Africa and Asia is well-known for its culinary and medicinal uses. The plant has received increasing interest due to its limonoid constituents. Phytochemical studies have led to the isolation and characterization of an array of bioactive compounds and pharmacological investigations have validated the traditional uses of the species as well as discovered some new bioefficacies. The aim of the review is to present an updated and comprehensive overview of traditional uses, ethnomedicinal significance, phytochemical and pharmacological aspects of F. jangomas to highlight its ethnopharmacological use and to explore its therapeutic potentials thereby providing a basis for future research. Relevant information and literature on F. jangomas from electronic databases such as Academic Journals, Google, Google Scholar, PubMed, Web of Science, and Science Direct were consulted and analyzed. Available literatures evidently demonstrate that F. jangomas possess a wide spectrum of pharmacological activities that could be explained by the presence of varied range of chemical constituents. Phytochemical and pharmacological investigations showed that extracts of different parts and major active components of F. jangomas had antimicrobial, analgesic, antidiabetic, antidiarrheal, antioxidant and cytotoxic activities. This emphasizes the need for further investigation to explore more bioactive chemical constituents and new bioefficacies of the plant and to establish a credible relationship between molecular structure and activity of compounds.

Authors and Affiliations

Sajeesha Sasi, Nishat Anjum, Y. C. Tripathi

Keywords

Related Articles

EVALUATION OF IMMUNOMODULATORY ACTIVITY OF EXTRACT FROM RIND OF NEPHELIUM LAPPACEUM FRUIT

Objective: Nephelium lappaceum Linn (Sapindaceae), also known as Rambutan is a tropical fruit native to Malaysia. The rind of Rambutan, which is normally discarded, has been used in the present research work to explore t...

DIELECTRIC RELAXATION STUDY OF BINARY MIXTURES AT DIFFERENT TEMPERATURES

Objective: The objective of this work is to study the intermolecular interaction and hydrogen bonding of the two binary mixtures at different temperatures which are determined from static dielectric constants and their e...

SIMULTANIOUS DETERMINATION OF ANTIRETROVIRAL DRUGS EMTRICITABINE AND TENOFOVIR DESOPROXIL FUMERATE BY A STABILITY INDICATING RP-HPLC METHOD

Objective: The objective of the present investigation is to develop a stability indicating RP-HPLC method for the simultaneous estimation of Emtricitabine (EMT) and Tenofovir Desoproxil Fumerate (TDF) in pure and tablet...

SYNTHESIS, ANTICANCER EVALUATION AND MOLECULAR MODELING OF SOME SUBSTITUTED THIAZOLIDINONYL AND THIAZOLYL PYRAZOLE DERIVATIVES

Objective: The present work aimed to synthesize some new substituted thiazoles incorporated to pyrazole moiety starting from 1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carboxaldehyde (1) in order to evaluate th...

FORMULATION AND EVALUATION OF PARENTERAL METHOTREXATE NANOLIPOSOMES

Objective: The objective of the present study was to encapsulate Methotrexate in liposomal formulation for treatment of cancer. Conventional compositions of Methotrexate are available but in high doses showvariation in b...

Download PDF file
  • EP ID EP567543
  • DOI 10.22159/ijpps.2018v10i3.23998
  • Views 86
  • Downloads 0

How To Cite

Sajeesha Sasi, Nishat Anjum, Y. C. Tripathi (2018). ETHNOMEDICINAL, PHYTOCHEMICAL AND PHARMACOLOGICAL ASPECTS OF FLACOURTIA JANGOMAS: A REVIEW. International Journal of Pharmacy and Pharmaceutical Sciences, 10(3), 9-15. https://europub.co.uk./articles/-A-567543