Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 diabetes mellitus
Journal Title: Polish Journal of Microbiology - Year 2016, Vol 65, Issue 1
Abstract
This is the first Romanian investigation of oral candidosis in patients suffering of HIV-infection or type 1 [i]diabetes mellitus[/i] (T1DM). [i]Candida albicans[/i] was the dominant species in both types of isolates: n = 14 (46.7%) in T1DM, n = 60 (69.8%) in HIV. The most frequent non-[i]albicans Candida [/i]spp. were [i]Candida kefyr[/i] (n = 6; 20%) in T1DM and [i]Candida dubliniensis[/i] (n = 8; 9.3%) in HIV. Resistance to fluconazole was detected only in the HIV non-[i]albicans Candida [/i]group (n = 8; 9.3%). All isolates were susceptible to VOR. The experimental drug MXP had MIC values equal or close to the ones of VOR. Echinocandin resistance was more frequent than azole resistance.
Authors and Affiliations
Bogdan Minea, Valentin Nastasa, Anna Kolecka, Magdalena Mares, Narcisa Marangoci, Irina Rosca, Mariana Pinteala, Monica Hancianu, Mihai Mares
Keywords
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