Euro-Collins Solution for a Lower-Cost Preservation of Donor’s Pancreas
Journal Title: Journal of Endocrinology and Diabetes - Year 2015, Vol 2, Issue 2
Abstract
This paper aims to evaluate results from pancreas-kidney transplants, in type 1 diabetes mellitus patients, comparing the use of Euro-Collins and Belzer or Celsior solutions for organ storage while awaiting transplant. One hundred and twenty two transplants were performed by the same transplant group, between November 2006 and June 2011. All pancreas grafts were perfused during the harvesting process through infusion of the aorta using standard solutions (Belzer or Celsior). Fifty-seven pancreas graft were stored in Euro-Collins solution (EC Group) and sixty six stored with Belzer or Celsior solutions (BC Group). The parameters analyzed were: postoperative complications, graft loss, mortality, hospitalization time and three-month follow-up period. The average cold ischemia time was 15.25 ± 1.98 hours in EC Group and 15.3 ± 2.66 hours in BC Group. The mortality rate was 15.8% in BC Group and 9.2% in EC Group. The loss of graft was 16.9% in EC Group and 8.8% in BC Group. The average hospitalization time was 13.8 days in EC Group and 18.4 days in BC Group. No significant statistical difference was observed in any parameters. It could be concluded that the use of Euro-Collins solution to store pancreas could be used without compromising the outcome of transplants.
Authors and Affiliations
Adriano Miziara Gonzalez, Rogério AokiFuziy, Enarco Grigolli Filho, Marcelo Moura Linhare, Alcides Augusto Salzedas Netto, Erika Rangel, Claudio Melaragno, Fernando Pompeu Piza Vicentine, Gaspar de Jesus Lopes Filho, Jose Medina de Osmar Pestana
Keywords
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- EP ID EP332951
- DOI 10.15226/2374-6890/1/2/00107
- Views 148
- Downloads 0
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