Evaluation of Anti-bacterial Activity of Silybum marianum against Pathogenic and Resistant Bacteria
Journal Title: European Journal of Medicinal Plants - Year 2016, Vol 13, Issue 4
Abstract
Aims: Our arsenal of antibiotics is running low due to overuse and misuse of these lifesaving drugs. Much research is needed on medicinal plants to look for drugs to tackle this issue Methodology: so antibacterial activity of organic extracts of Silybum marianum was evaluated against Methicillin-resistant Staphylococcus aureus (MRSA), resistant E. coli, ATCC 12361, ATCC 12466 and ATCC 13581. Inhibition of bacterial growth was determined using agar well diffusion methods. Results: Among all assayed organic extracts only Dimethylformamide presented highest activities against all tested strains except resistant E. coli. Dimethylformamide and Methanol showed better activity than cephradine against ACTT 13581. The Dichloromethane extract showed no antibacterial activity against any strains. Methanol and Isopropyl Alcohol showed moderate activities against all tested strains. S. marianum would be an interesting topic for further study and possibly for an alternative treatment for resistant and pathogenic bacterial infections.
Authors and Affiliations
Amoos Bajwa, Sheraz Tariq, Alamgeer Yuchi, Rizwan Hafeez, Amna Arshad, Muhammad Zaman, Tahir Aqeel, Muhammad Naveed Mushtaq
Alternative to Conventional Diabetic Management: The Antihyperglycaemic potential of an Ethyl Acetate Fraction Extract of Holarrhena floribunda
Aims: Antihyperglycaemic effects of an ethyl acetate fraction of the leaf extract of Holarrhena floribunda on normal and streptozotocin-induced diabetic rats. Study Design: Healthy adult albino Wistar rats (weighing 100-...
Bioassay-Guided Discovery of Antibacterial Agents: In vitro Susceptibility of Multi-drug Resistant Staphylococcus aureus to Psidium guajava Linn Extracts
Aims: Development of multi-drug resistance to antibiotics is a major health concern worldwide. This study assessed the antibacterial activities of leaves extracts from Psidium guajava against multi-drug resistant Staphy...
Evaluation of Hepatoprotective Effect of Methanol Extract of Solanum melongena on Carbon Tetrachloride Induced Hepatotoxic Rats
Aim: To evaluate the effect of methanol extract of Solanum melongena on carbon tetrachloride- induced liver damage in albino rats. Methodology: The qualitative and quantitative phytochemicals screening of the plant extr...
Antimicrobial Activities of Six Selected Plants against Multi-drug Resistant Staphylococcus aureus
The problem of microbial resistance is growing and the outlook for the success of antimicrobial drugs in the future is still uncertain. For a long period, plants have been a valuable source of natural products for mainta...
Toxicity Studies on Anti-fungal Essential Oils Extracted from Selected Aromatic Plants from Mabira and Kakamega Forests, East Africa
Aim: In a bid to explore for grain bio-preservatives, essential oils extracted from Cymbopogon citratus, Rosmarinus officinalis, Monanthataxis littoralis and Aframomum angustifolium, that were earlier established to have...