Evaluation of anti-fungal activity of Chakramarda Seeds (Alcoholic extract) on Clinical Pathogens (Dermartophytosis)
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2017, Vol 0, Issue 0
Abstract
Dermatophytoses have become a significant health problem affecting children, adolescents and adults world-wide. In India 5 out of 1000 people suffer from Tinea infections. In the present study evaluation of antifungal activity of Chakramarda on Tinea (Dermatophytoses) was performed and for the same culture and sensitivity skin scrapping samples were collected from the edge (active border area) of lesions. Culture was done by collected skin scrapping of patient suffering from Dadru Kushta. Sabouraud’s dextrose agar (SDA) slant media was inoculated via sterile technique and culturing was done by streak culture method and it was subjected to macroscopic and microscopic examination for the identification of fungi. Sensitivity test was done using SDA media by Cork Borer well diffusion method, with five different concentrations of alcoholic extracts of Chakramarda seeds. After the incubation period, the zone of inhibition was measured in mm. Experimental study with five different concentrations (1.25µl, 2.5µl, 5µl, 10µl, 20µl) of Alcoholic extract of Chakramarda showed progressive increase in zone of inhibition with increase in concentration. Therefore, it was concluded that as concentration of Chakramarda drug increases the antifungal activity also increases. Alcoholic extract of Chakramarda seeds has anti-fungal (Krimighna) action against Dermatophytoses (Tinea).
Authors and Affiliations
Anoma Geethani Samarawickrama, Ajantha . , Shashirekha K S, Chethana Kumari D. S
Keywords
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