Evaluation of Anti microbial Activity of Extracts of Pedalium murex
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2017, Vol 5, Issue 4
Abstract
As part of search for new biological active compounds from higher plants the crude organic extracts of Pedalium murexas screened. The purpose of this study was to investigate Indian plants potential antibiotic activity by preliminary bio-screening. That is why to evaluate the anti- bacterial potential of different extracts of Pedalium murex was carried out. .In the present study, extracts of Pedalium murexwas evaluated for preliminary phytochemical screening and antibacterial and antifungal activity. The various extracts of the powdered leaves of Pedalium murex (L.) were subjected to anti-bacterial studies one gram+ve and one gram-ve bacteria. The organisms used were Staphylococcus epidermidis (gm+ve) and Escherischia coli (gm-ve) and for evaluation of anti-fungal studies against the fungi like Candida albicans and Aspergillus niger are taken. The organisms were maintained on sabouraud’s broth. Different extracts were tested at dose 40 mg/ml for both bacteria and Fungi where ciprofloxacin and ketoconazole were taken as standard respectively. The results showed among of all extracts ethanolic extract possess good antimicrobial activity against bacteria and fungi when the zone of inhibition is evaluated after 24 hrs of incubation at 370C.
Authors and Affiliations
Upadhayay Ashutosh, Singh Yogender, Bhupendra Kumar Kumawat
Keywords
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