EVALUATION OF ANTIBACTERIAL RESISTANCE OF BIOFILM FORMS OF AVIAN SALMONELLA GALLINARUM TO FLUOROQUINOLONES
Journal Title: Universal Journal of Pharmaceutical Research - Year 2018, Vol 3, Issue 4
Abstract
Antimicrobial resistance is a growing concern worldwide. The indiscriminate use of antibiotics for a period of time has led to the emergence of antibiotic resistance in pathogenic bacteria. The present study was designed to evaluate the antibacterial efficacy of fluoroquinolone drugs, ciprofloxacin, enrofloxacin, moxifloxacin, sparfloxacin, norfloxacin, pefloxacin and ofloxacin against avian Salmonella gallinarum bacterial biofilms. The study parameters, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and biofilm elimination concentration (BEC) were determined on days 1, 3, 7, 10, 14 and 20 post inoculation for the planktonic (free) and biofilm cells of S. gallinarum by macro broth dilution method. The MIC and MBC values determined on days 1, 3, 7, 10, 14 and 20 for each of the fluoroquinolone drugs against the planktonic and biofilm forms of avian S. gallinarum were found to be non-significant. BEC values determined against the biofilm forms of S. gallinarum during the study period were found to be non-significant among the tested fluoroquinolones. The results of the present study demonstrated that fluoroquinolone drugs were effective in vitro against both the planktonic and biofilm forms of avian S. gallinarum.
Authors and Affiliations
Kumar Kamashi, Mr. Honnegowda, Mayanna Asha, Chandrakala Ms.
Keywords
Related Articles
- EP ID EP36473
- DOI https://doi.org/10.22270/ujpr.v3i4.175
- Views 329
- Downloads 0
Editorial..
It is great honor and privilege for me to be appointed as Member - Editorial Board, Universal Journal of Pharmaceutical Research (UJPR). My heartiest salutations to Prof. Dr. Kapil Kumar, Editor-in-Chief and the other bo...
PREVALENCE OF HEPATITIS G VIRUS AMONG PATIENTS WITH CHRONIC LIVER DISEASE AND HEALTHY INDIVIDUALS, SANA'A CITY-YEMEN
Hepatitis G virus (HGV) is a newly discovered and enveloped RNA positive-stranded flavivirus-like particle, which has not yet been proven to have major negative effects on liver. Therefore, it is important to estimate th...
THE ROLE OF DIGITAL MARKETING IN MEDICAL TOURISM INDUSTRY IN POINT OF VIEW OF MEDICAL TOURISM POLICY MAKERS OF SHIRAZ IN 2017
Medical tourism refers to traveling to places where the individual could use medical services. Therefore, such a travel requires various activities in any of which the individual health is considered. Main samples of the...
Editorial Message..
I would like to deeply congratulate all the Universal Journal of Pharmaceutical Research team for completing 3 successful years since the rise of the journal. It was an honor to join the UJPR team as a member in the Edit...
DEVELOPMENT AND EVALUATION OF ALBENDAZOLE MICROCAPSULE FOR COLONIC DRUG DELIVERY SYSTEM
At present scenario colon specific drug delivery has gained increased importance. Colon drug delivery system not only used for the treatment of local diseases, associated with the colon but also it is a potential site f...