Evaluation of antistress activity of Cassia auriculata seed extract
Journal Title: The Journal of Phytopharmacology - Year 2018, Vol 7, Issue 2
Abstract
Objective: The present study was designed to investigate the anti-stress activity of Cassia auriculata ethanolic seed extract in mice. Methodology: The anti-stress effect was evaluated by using Elevated plus maze (EPM), Force swimming test (FST) and Tail suspension test (TST). The ECS at a doses (250,500 and 1000 mg/kg p.o.) and standard (diazepam 2 mg/kg i.p and fluoxetine 20 mg/kg i.p) was administered. Results: The extract showed the increased in the number of entries and time spent in open arm in Elevated plus maze and decreased in the immobility time in both Force swimming test and Tail suspension test. Conclusion: The effect of ESC on animal behavior was concordant with a significant regulation of GABA and stress hormones. Therefore, this study was attempted to demonstrate the preventive potential of ECS against stress disorders at in vivo levels.
Authors and Affiliations
Shravan Kumar Nanumala, B. Varsha priyanka, N. Divya, S. Shalini, S. Sanjay singh, T. Haripriya
Keywords
Related Articles
- EP ID EP49805
- DOI -
- Views 184
- Downloads 0
Anti-tussive activity of Shwasakuthara Rasa a Herbomineral formulation prepared with and without Kajjali (Black Sulphide of Mercury) in SO2 induced cough in Swiss albino mice
Introduction: Kajjali is considered as the base in maximum Rasa Yogas (Herbo-mineral formulations). Shwasakuthara Rasa (SKR) is a well-known herbo-mineral formulation indicated in different kinds of Shwasa (respiratory...
Anti-inflammatory and safety assessment of Polyscias fruticosa (L.) Harms (Araliaceae) leaf extract in ovalbumin-induced asthma
Background: Polyscias fruticosa is a plant used in the traditional management of asthma in Ghana. Aim: This study evaluated the anti-inflammatory property of an ethanolic leaf extract of Polyscias fruticosa and safety...
Nephroprotective acitvity of Amomum subulatum seeds against cypermethrin induced nephrotoxicity in rats
The objective of the present study was to evaluate nephroprotective activity of Amomum subulatum seed extract against Cypermethrin induced nephrotoxicity in albino rats. The animals were divided into five different gro...
Susceptibility of two maize grain flour to infestation by the rust- red flour beetle (Tribolium castaneum Herbst)
The susceptibility of white and yellow maize grain flour to Tribolium castaneum was evaluated at ambient temperature and relative humidity in the laboratory were 33.6±0.21 0C and 35.8±0.13% RH. Different quantities of...
Protective effect of Mollugo cerviana extract on liver markers in alloxan induced diabetic rats
Diabetes mellitus is a metabolic disorder of multiple aetiology characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin...