EVALUATION OF CARCINO EMBRYONIC ANTIGEN (CEA) AND CARBOHYDRATE ANTIGEN (CA19-9) IN MONITORING OF TREATMENT RESPONSE IN GASTROINTESTINAL CANCERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 51
Abstract
BACKGROUND Carcino Embryonic Antigen (CEA) and Carbohydrate Antigen 19-9 (CA 19-9) were two tumour markers frequently used in the diagnosis, and monitoring of treatment response of gastrointestinal cancers like colon, rectum, stomach, pancreas and gall bladder cancers. MATERIALS AND METHODS This study is a case-control study. 50 diagnosed and confirmed cases of gastrointestinal cancers attending the surgery outpatients department and wards of Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India from March 2015 to February 2018 form the study group. CEA and CA19-9 estimation was done before the start of any treatment, during treatment and after treatment; may it be Surgery, Radiotherapy or Chemotherapy. The usefulness of these two tumour markers, CEA and CA19-9 combined for monitoring the treatment response was evaluated. RESULTS It is found that the combined use of these two markers CEA and CA19-9 is much more useful for monitoring of treatment response in the patients of gastrointestinal cancers when compared to the use of CEA alone or CA19-9 alone. CONCLUSION It is found that the combined use of these two markers CEA and CA19-9 is much more useful for monitoring of treatment response in the patients of gastrointestinal cancers when compared to the use of CEA alone or CA19-9 alone.
Authors and Affiliations
Rosemary Vumkhoching, Yengkhom Sanatomba Singh, Dhanabir Thangjam, Ningombam Jitendra
Keywords
Related Articles
- EP ID EP550476
- DOI 10.14260/jemds/2018/1209
- Views 74
- Downloads 0
A SYNDROME OF EXTENSIVE PERIPAPILLARY MYELINATED NERVE FIBRES, HIGH IPSILATERAL MYOPIA AND REFRACTORY AMBYLOPIA
Myelinated retinal nerve fibers are rare developmental anomalies present in 0.5- 1% of all eyes. Occur due to myelination of ganglion cells beyond the lamina cribrosa during embryonic development. Reports of am...
CONSERVATIVE MANAGEMENT OF TRAUMATIC BRAIN INJURY
BACKGROUND Traumatic brain injuries are a major cause of morbidity and mortality in modern times and it is a huge health sector burden.[1] Understanding the mechanism of traumatic brain injury leads to the development of...
SERUM MAGNESIUM IN CRITICALLY ILL PATIENTS AND ITS CORRELATION WITH OUTCOME
BACKGROUND Hypomagnesaemia is an emerging electrolyte disturbance in hospitalised patients, especially in critically ill ones and it has been shown to predict mortality in intensive care units (ICUs). This study was aime...
STRANGE BEDFELLOWS- PROSTATOMEGALY, CHOLELITHIASIS AND METABOLIC SYNDROME COMPONENTS- IS THERE A CORRELATION?
BACKGROUND As life expectancy goes up, a noticeable increase in ageing populations are seen in both developed as well as developing nations. Prostatic enlargement and cholelithiasis are important causes of morbidity in t...
TENSION FREE ONLAY VENTRAL HERNIA REPAIR BY POLYPROPYLENE MESH- A NEWER APPROACH
BACKGROUND Ventral Hernia repair remains one of the most commonly performed surgical procedure. Operations for ventral hernia were notorious, because of high failure rate. With continued improvement of the materials and...