Evaluation of cardiac autonomic functions of non diabetic offsprings of diabetic parents
Journal Title: Indian Journal of Clinical Anatomy and Physiology - Year 2018, Vol 5, Issue 3
Abstract
Occurrence of autonomic imbalance is not very uncommon in diabetic patients and evidences of subclinical autonomic imbalance in their offsprings are also reportedObjective To study the effect of parental diabetes on cardiac autonomic functions of their non diabetic childrenaterials and Methods The study was conducted in the department of Physiology SSIMS and RC Davangere after the approval of the institutional ethical committee on 100 subjects 50 non diabetic offsprings of diabetic parents cases and 50 non diabetic offsprings of non diabetic parents controls The subjects were in the age group of 1825 years and were selected on the basis of predetermined inclusion exclusion criteria The study protocol was explained and informed written consent was taken from the subjects Battery of six conventional cardiac autonomic function tests were done which included resting HR HR response to deep breathing HR response to Valsalva DBP response to IGHT BP and HR response to change in posture BP response to CPT Statistical analysis was done using Students unpaired t testResult Our results show decreased parasympathetic activity as indicated by increased basal HR p 0Conclusion Our results show that there is a state of sympathovagal imbalance in the non diabetic offsprings of diabetic parents that can be inferred from an increased sympathetic activity and decreased parasympathetic activityKeywords Diabetes mellitus Autonomic function
Authors and Affiliations
Mehak Mufti, Ravikiran Kisan, D. V. Deshpande
Keywords
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- EP ID EP476113
- DOI 10.18231/2394-2126.2018.0090
- Views 81
- Downloads 0
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