Evaluation of Clinical Profile and Etiology of Pancytopenia in Adults Above 18 Years
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Background: Pancytopenia is an important challenge in our routine clinical practice by hematological entity. There are different swing in its pattern, treatment procedures, and outcome. The aim of this study to evaluated the etiological & clinical profile of pancytopenia in adults above 18 years and its better understanding. Material & Methods: A Prospective Hospital Based Study conducted on 100 Cases in the age group above the 18 years with pancytopenia attended in medical OPD in MGMCH, Jaipur during the period of December 2015 onwards. Patient showing parameters as haemoglobin < 9 g/dl, TLC <4X109 and Platelet count < 140X109/ L with reference to age and geographical areas were included in this study. Results: Our study showed that the 55% incidence of pancytopenia was present in18-35 years of age group and male to female ratio was 1.7:1. All patients have clinical presentation was pallor, followed by 96% generalized weakness, 92% anorexia, 91% fatigability. The incidence of macrocytic anaemia was (67%) more in peripheral blood film and normocellularity is the commonest association constituting 71% followed by Megakaryocytic (21%) in bone marrow examination. Conclusion: The physical findings and peripheral blood picture provides precious information in the work of pancytopenia patients. Complete hematological examination including bone marrow aspiration should be done in pancytopenia patients to recognize and diagnose this disease early so that proper intervention and medical treatment of these patients can be done.
Authors and Affiliations
ShivJeet Yadav, H. P Paliwal, Anchin Yadav, Aashish Sharma
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