Evaluation of cytotoxicity of polyetheretherketone (peek) as A dental implant material
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2018, Vol 10, Issue 3
Abstract
Purpose: PEEK (polyetheretherketone) is a synthetic polymer being used increasingly as a dental implant material due to its iso-elastic nature and enhanced mechanical properties. This study analysed the cytotoxicity and biocompatibility of PEEK which helps to improve its bioactivity and ensure widened clinical prospects in future. Methods: Samples of PEEK dental implant material were added to murine T3T fibroblasts which were cultured in Dulbecco’s modified eagle medium at 37ºc. After 24 hours incubation at 37ºc and 5% carbon dioxide, the medium was replaced with 200 micro litre of medium which contained extracts of PEEK implant material. Cell morphology was analysed using Motic Inverted Microscope. Results: The result for biocompatibility of PEEK as a dental implant material when evaluated using Colony-forming unit fibroblast assay, was positive showing no signs of cytotoxicity. Conclusion: With analogous physical and mechanical properties to bone, PEEK has proved to be a potent biocompatible dental implant material.
Authors and Affiliations
Dr. Rhea Mahajan . , Dr. Roseline Meshramkar . , Dr. Lekha, KP . , Dr. Ramesh Nadiger . , Dr. Sandeep Mahajan .
Keywords
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