Evaluation of first trimester fasting blood glucose as a predictor of gestational diabetes mellitus
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2017, Vol 4, Issue 1
Abstract
Background: Our goal was to find association between first trimester fasting blood sugar value compared with the second trimester oral glucose tolerance test value (75gm DIPSI criteria) for diagnosis of GDM. To find the efficiency of FBS and BMI as a screening test for GDM. Material and Method: 270 antenatal patients having antenatal follow up from 1st trimester of pregnancy between June 2014 – May 2015. The study period was 12 months. Their fasting blood glucose levels was measured in first trimester. The patients were followed up during second trimester and 75 grams OGTT was done. Correlation between first trimester FBS, BMI versus second trimester OGTT were done. Screening property of both fasting blood sugar and BMI were calculated and compared using receiver operating characteristic (ROC) curves. Result: Out of 270 patients, 14 patients developed GDM, 1 patient developed overt diabetes. With threshold of FBS>90 yielded sensitivity of 86%, specificity of 52%. FBS >90mg/dl can be considered as a threshold value for predicting GDM. With a threshold of BMI>24 yielded sensitivity of 60%, specificity of 67.5%, hence BMI >24 is a good predictor of GDM. Receiver operating characteristic curve shows FBS(AUC-0.69) has little more discriminatory power in identifying GDM than BMI(AUC=0.63). P value <0.05 was considered statistically significant. Conclusion: In conclusion, FBS measurement at first prenatal visit or at first booking will be useful to screen for previously undiagnosed pre-existing diabetes mellites and also help to predict the development of GDM earlier.
Authors and Affiliations
Reshma Shri Aravind, Latha Maheshwari, Aravind Chander
Keywords
Related Articles
- EP ID EP313023
- DOI 10.18231/2394-2754.2017.0014
- Views 88
- Downloads 0
Effect of Yoga exercises on the course of pregnancy, labour and puerperium
Introduction: Pregnancy is a condition in which women undergo distinct physiological changes and stress. Also accompanied by unique physical and psychological demands, Yoga is thought to alter nervous system regulation a...
Outcome of immediate postpartum insertion of IUCD - A prospective study
Introduction Immediate postpartum intrauterine contraceptive device insertion is an excellent family planning method which provided safe effective long term and reversible contraception to women in the delivery setting H...
Maternal and fetal outcome in eclamptic convulsion with Magnesium sulphate therapy
Eclampsia accounts for 50,000 maternal deaths a year worldwide. The maternal case fatality rate is 1.8% and 35% of eclamptics will have one major complication. Objective: objective of study was to improve maternal and fe...
A school-based survey of premenstrual dysphoric disorder-relationship with depression, anxiety, self-esteem and quality of life
Introduction Premenstrual dysphoric disorder PMDD is a severe and debilitating form of Premenstrual syndrome PMS affecting women in their reproductive age There is paucity of Indian research in this area among adolescent...
Maternal complications of hypertension in pregnancy – A five year study
Introduction Hypertension is the most common medical problem encountered in pregnancy Approximately 18 of maternal deaths worldwide are due to hypertension complicating pregnancy For every woman who dies it is estimated...