Evaluation of Gastrointestinal Cause in Cases of Unexplained Anemia in Adults - A Study from Tertiary Care Center
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 4
Abstract
Background: Anemia is the most common illness, the human being is suffering even on today. About 50% of Indian population suffer from this disease. Evaluation of anemia is the most important step in the management. Blood loss from gastrointestinal (GI) tract is one of the common causes of anemia in adults, but its evaluation is expensive and multistep procedures. On the contrary, if there is delay in evaluation, it may be too late to offer the optimal therapy. Aims and Objective: The aim of this study is to evaluate the profile of GI disorders in unexplained anemia in adult patients and need of its evaluation. Materials and Methods: A total of 146 patients with the unexplained anemia attaining Clinical Haematology Department of SCB Medical College, Cuttack, from January 2014 to January 2017 were taken in the study. A detailed GI evaluation was done in all cases. All the analyses were done in SPSS 17 software. Results: A total of 46 cases responded to treatment after addressing to known primary etiology. A total of 100 cases did not respond to treatment and underwent further evaluation in the present study. The mean age was 50 years (range 15-72 years). Male-to-female ratio was 1.086. The mean duration of the illness was 8 months, and the mean hemoglobin was 7.2 g/dl (range 4.5-9 g/dl). Among 100 patients not responding to treatment, GI causes for anemia found in 50 (50%) patients, 10 (10%) patients had a disease outside GI tract, and in 40 (40%) patients no cause for anemia established. GI malignancy was the most common finding (26%) followed by chronic duodenal ulcer and ileocecal tuberculosis. Conclusions: GI disorders are the leading cause of unexplained anemia in adults (50%). Malignancy was identifying as the most common cause with colon and stomach being the frequent sites of involvement, followed by benign etiology with chronic duodenal ulcer and ileocecal tuberculosis. We strongly recommend a thorough GI evaluation in this subset of unexplained anemia of adult patients.
Authors and Affiliations
Chitta Ranjan Panda, Kali Prasanna Swain, Sambit Kumar Behera, Rabindra Kumar Jena, Tapan Kumar Sahoo
Keywords
Related Articles
- EP ID EP473032
- DOI -
- Views 127
- Downloads 0
Prospective Study of Stab Injury of Abdomen
Background: Stab wound has been rising at a phenomenal rate and has become a source of worry for the society. Stab wound is more commonly encountered in urban population then rural. Aims and Objectives: (1) Epidemiologic...
A Gender-based Comparative Study of Visual and Auditory Reaction Time on 1st Year Medical Students “Before” and “After” Caffeine Intake
Introduction: The present study is a gender-based comparison of the auditory and visual reaction time (RT) in male and female 1st year medical students, before and after the administration of caffeine present in coffee....
Patient’s Profile of Foreign Body in the Esophagus
Introduction: Foreign body in the esophagus is one of the most common cases found by ENT experts. Purpose: The purpose of the research is to obtain patient’s profile of foreign body in the esophagus in the Department of...
Comparative Evaluation of Marginal Microleakage of Conventional Fissure Sealants and Self-adhering Flowable Composites as Fissure Sealant in Permanent Teeth - An In Vitro Study
Background: Sealant therapy is the safe and effective way to prevent dental caries in newly erupted teeth. Success of sealant therapy depends on the good isolation, patient corporation and the decrease step for the appli...
Role of Platelet-rich Plasma on Nasal Mucociliary Clearance after Septoplasty - A Randomized Clinical Study
Background: Intranasal surgeries include septoplasty, endoscopic sinonasal surgeries, and endonasal dacryocystorhinostomy for different indications. During the post-operative period, the patients frequently encounter pro...