Evaluation of phytochemicals, antioxidants and anti-inflammatory activity of fresh leaf and flower extracts of Tagetes erecta L. grown in Kalaburagi
Journal Title: International Journal of Life Science - Year 2018, Vol 6, Issue 2
Abstract
Tagetes erecta L. (Asteraceae) is used to treat epileptic fits (Ayurveda), fever, wounds and microbial infections of livestock’s in folklore medicine of Kalaburagi district. As little work has been carried out on fresh material so present study aims to evaluate aqueous extracts of fresh leaf and flower for phytochemicals, antioxidants and anti-inflammatory activities. The results revealed that the leaf extract was rich in primary as well as secondary metabolites as compared to flower extract. The physicochemical analysis such as moisture, crude fat, crude fibre content and total ash values found higher in leaf extract than flower extract. The DPPH and Nitric oxide radical scavenging activity found higher in flower extract than the leaf extract when compared to standards. Whereas the Hydrogen peroxide and Reducing power assay of leaf extract showed higher activity than flower extract at different concentrations. Anti-inflammatory activity showed that the HRBC membrane stabilization activity of leaf extract was found higher than flower extract and albumin denaturation activity of flower extract was found higher than leaf extract. From the study it is evident that the fresh leaf and flower extracts of Tagetes erecta are effective source of naturally and pharmacologically active compounds which can be used in herbal remedies.
Authors and Affiliations
Manjula A1 Rathod, Pratima Mathad
Keywords
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