EVALUATION OF SAFETY AND EFFICACY OF POLYHERBAL FAIRNESS CREAM
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 1
Abstract
Fair skin has always been the desire of people since ages and has been associated with beauty. Earlier, most of the people used homemade (turmeric, milk, honey) products and lotions to make their skin lighter in shade. With the assumption of fair skin as a sign of beauty, there has been bias for the skin colour in most of the countries. People use fairness cream to improve their complexion, irrespective of whether they have dark or fair complexion. The purpose of this open prospective, non-comparative Phase III clinical trial was to evaluate the safety and efficacy of Polyherbal Fairness Cream as a result of repeated application for 4 weeks. Fifty subjects were included in this study. They were advised to apply fairness cream twice daily for a period of 30 days. All the patients were followed-up at weekly intervals for a period of 4 weeks. Response to Fairness Cream was evaluated on a 5-point visual analogue scale. All subjects completed the study and significant reduction in dark complexion, increase in skin softness, and skin glowing effect was seen at the end of the study. There were no adverse effects reported during the study and compliance to the use of formulation was excellent.
Authors and Affiliations
Hardik K. Soni , Vishal J. Gandhi , Surendra B Bhatt , Urvashi D. Shah , Vaishali N. Shah
DEVELOPMENT AND VALIDATION OF A GREEN BIOANALYTICAL METHOD FOR THE DETERMINATION OF SPARFLOXACIN IN PHARMACEUTICAL DOSAGE FORM AND HUMAN PLASMA BY RP-HPLC
This study describes the development of an innovative, green, rapid, precise, selective and sensitive reverse phase high-performance liquid chromatography method for the quantitative determination of Sparfloxacin (SPR) i...
PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND ANTHELMINTIC ACTIVITY OF ACACIA SUMA (ROXB) BARKS
The present work was conducted to investigate the preliminary phytochemical studies and anthelmintic activities on the bark of Acacia suma (Roxb.) Family- Fabaceae against adult Indian earthworms, Pheretima posthuma. Var...
PREPARATION AND IN VITRO DRUG RELEASE OF SODIUM DICLOFENAC NANOPARTICLES USING MEDIUM CHAIN CHITOSAN AND TRIPOLYPHOSPHATE
Diclofenac sodium is a non-steroid anti-inflammatory drug for inflammation, analgesic and antipyretic. To obtain optimal therapeutic effects, diclofenac sodium has several drawbacks, e.g. high adverse effects, undergoes...
MICRONEEDLES IN TRANSDERMAL DRUG DELIVERY: AN UNIQUE PAINLESS OPTION
The outermost layer of skin, the stratum corneum, has developed unnerving physical and immunological barrier properties that prevent infiltration of noxious chemicals and pathogens. Consequently, transdermal delivery of...
ASYMPTOMATIC BACTERIURIA AMONG PREGNANT WOMEN ATTENDING THE OUTPATIENT CLINIC OF CHITWAN MEDICAL COLLEGE TEACHING HOSPITAL, CHITWAN, NEPAL
Urinary Tract Infection (UTI) refers to both microbial colonization of the urine and tissue invasion of any structure of the urinary tract. Pregnancy enhances the progression from asymptomatic to symptomatic bacteriuria...