Evaluation of selected indicators of antioxidant status in patients with head and neck cancer
Journal Title: Otolaryngologia Polska - Year 2015, Vol 69, Issue 5
Abstract
Introduction: The aim of the study was to evaluate the severity of lipid peroxidation (TBARS) and enzymatic antioxidant barrier in red blood cells of patients suffering from cancer of the head and neck and the healthy individuals. Material and methods: In the blood of 22 patients and healthy volunteers determined superoxide dismutase, catalase, glutathione peroxidase and malondialdehyde by the spectrophotometric method. Results: It was found decreased activity of SOD, CAT, GPx and an increase of MDA concentration in patients with cancer compared to the control group. Discussion: The level of lipid peroxidation in erythrocytes of patients indicates an intensification in their process, and the results clearly demonstrate that enzymatic antioxidant system weakness. However, the presented results are pilot character, were conducted on a small group of subjects, and it seems necessary to expand research panel to genetic and non-genetic factors.
Authors and Affiliations
Hanna Zielińska-Bliźniewska, Małgorzata Mrowicka, Jurek Olszewski, Ireneusz Majsterek
Keywords
Related Articles
- EP ID EP76608
- DOI 10.5604/00306657.1163579
- Views 108
- Downloads 0
A rare case of plasmocytoma of uvulae and carcinoma of larynx
Plasmocytoma solitare is a rare disease of lymphoprolipherative origin. It is usually diagnosed occasionally on ORL departaments because of its close relation to head and neck localisation. Surgical treatment and/or radi...
Tor oddechowy a jakość życia u pacjentów z zaburzeniami drożności nosa
Wprowadzenie: Niedrożność nosa jest częstym objawem występującym w populacji, jednak obiektywna ocena tego symptomu jest trudna. Badanie fizykalne, tomografia komputerowa, rynometria akustyczna i rynomanometria nie odzwi...
Chirurgiczna rehabilitacja głosu chorych po laryngektomii całkowitej z zastosowaniem systemu Provox
The aim of study. Comparison the voice quality of patients after total laryngectomy using the Provox 2 voice prosthesis and patients with esophageal speech and to discuss difficulties and complications related with its i...
Subjective interaoperative hearing self-assessment in patients after stapedotomy comparing to postoperative pure-tone audiometry
In otosclerosis patients the most common procedure followed at Otosurgical Dept. Medical University of Lodz is stapedotomy with insertion of teflon-piston prosthesis. When surgery is finished a whisper hearing test is do...
Antybiotykoterapia dla laryngologa
W opracowaniu dedykowanym głównie ogólnie praktykującym laryngologom omówiono zasady antybiotykoterapii najczęstszych schorzeń jakimi zajmuje się ta specjalność a mianowicie ostrym zapaleniem migdałków podniebiennych i g...