EVALUATION OF SERUM ALKALINE PHOSPHATASE AND CALCIUM IN PREMENOPAUSAL AND POSTMENOPAUSAL SUDANESE WOMEN
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 6
Abstract
Background: Menopause is a permanent cessation of menses resulting from reduced ovarian hormones secretion that occurs naturally or induced by surgery, chemotherapy or radiation. The aim of this study is to estimate serum alkaline phosphatase and calcium in pre and post-menopausal women, compare the two levels and evaluate the need of calcium supplementation in study population. Methodology: the present study was carried out on 80 total subjects divided into two groups 40 women were pre menopause and the rest were post menopause. Alkaline phosphatase was measured by kinetic method and calcium was measured by ortho- cresolphathlein complex method. Results: the result of calcium and alkaline phosphatase showed statistically significant difference between pre and post-menopausal women with p.value (0.000 and 0.000) respectively. Conclusion: The Increasing in bone turnover activate reduction in bone mass. Our study suggest that post-menopausal women have to take calcium rich foods to maintain normal level of calcium and if foods are not available or serum still low supplementation by tablets alternative.
Authors and Affiliations
Rua Hashim Yousuf
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