Evaluation of Spermatotoxic Effect of Sweet Potato (Ipomoea batatas) Leaf Extract on Male Albino Rats
Journal Title: Asian Journal of Biotechnology and Bioresource Technology - Year 2017, Vol 1, Issue 1
Abstract
Aim: The study examined the effect of sweet potato (Ipomoea batatas) leaf extract on the sperm toxicity and weight of testes and epididymes in male albino rat models. Methodology: This study was carried out in the Animal house of the Department of Genetics and Biotechnology, University of Calabar, Calabar and lasted for 65 days. Twenty four male rats were randomly divided into four groups of six rats each using a completely randomized design. Group A served as control and received only water and pellet feed while group B, C and D received 200 mg/kg, 400 mg/kg and 600 mg/kg body weight of the aqueous extract of Ipomoea batatas leaf, respectively. Results: Results obtained revealed a significant (P= .05) decrease in the weight of epididymes, sperm motility, sperm viability and sperm count while sperm head abnormalities significantly increased in the extract – treated animals. No significant differences were observed in semen pH and weight of testes. Conclusion: The findings of the study suggest that aqueous extract of I. batatas leaf has spermatotoxic effect on the male albino rats in a dose – dependent manner.
Authors and Affiliations
U. U. Uno, C. M. Okolo, H. O. Ogbe, U. B. Ekaluo, M. E. Benjamin
Keywords
Related Articles
- EP ID EP337883
- DOI 10.9734/AJB2T/2017/35749
- Views 92
- Downloads 0
Evaluation of the Phytochemical Composition and Pasting Characteristics of African Locust Bean Pulp Flour, Wheat Flour and Blends
Aim: The study determined the phytochemical composition and pasting properties of locust bean pulp, wheat flour and the blends. Study Design: The experiments in carried out in three replications in completely randomized...
In vivo Germination of Encapsulated Orchid Seeds of- Epidendrum radicans
The orchid seeds are naked embryos without any nutritive tissue to support them for germination in vivo. In nature, they germinate symbiotically when they come in contact with mycorrhiza found in the mother root tufts. O...
Optimization of Extraction Procedure for Isolation, Identification & Quantification of Piperine from Roots of Piper longum Linn.
Aim: Piperine which is mainly found in the fruits and roots of the Piper longum plant and is a medicinally active bio-molecular compound, used as potential ingredient in preparation of several medicines. This present stu...
Phytochemical Components, Antioxidant and Cytotoxic Activities of Mulberry Mistletoe (Loranthus parasiticus Merr) Leaves Extracts
Herein, we investigated the effects of solvents on the phytochemical components, antioxidant activities, and cytotoxicity of Mulberry mistletoe leaves. An FT-IR method was performed to identify the essential functional g...
Efficacy of Lippia multiflora (Verbenaceae) and Hyptis suaveolens (Lamiaceae) Leaves on Sanitary Quality during the Storage of Maize Grain (Zea mays L.) from Cote D’ivoire
The aim of this study was to monitor the sanitary quality during the storage of maize grains for 9 months in polypropylene bags containing leaves of Lippia multiflora and Hyptis suaveolens. It was carried out in the vil...