Evaluation of the Efficacy of Tamsulosin and Deflazacort versus Tamsulosin Alone in Expulsion of Lower Ureteric Stones in a Tertiary Center
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2019, Vol 6, Issue 10
Abstract
Introduction: Urolithiasis is a very common problem present. About 70% of all ureteric stones are found in the lower third of ureter. Many factors affect the modality of treatment such as setup available, type, size of stone and expertise of the surgeon. Extracorporeal shock wave lithotripsy and ureteroscopy and removal of stone are very effective, but they require the help of anesthetist. Ureter is to be stented, and the stent has to be removed later on. They are very costly and not without complications. Many pharmacological agents have been used for the expulsion of ureteric stones, for example, diclofenac, alkalizers, ketorolac, nifedipine, deflazacort, prazosin, silodosin, and tamsulosin. Materials and Methods: This prospective observational study was conducted in the Surgery Department at SGT Medical College. A total of 100 patients of distal ureteric stones of sizes 4–10 mm were taken in this study, divided into two groups of 50 patients each. Group I patients were given tamsulosin 0.4 mg and deflazacort 30 mg once in a day, Group II patients were given tamsulosin 0.4 mg once in a day. Treatment was for 10 days. Results: In Group I, the stones were expelled in 38 (76%) patients, while in Group II, 26 (52%) patients passed stones. This is statistically significant with P = 0.038. The median time for stone expulsion was 3 days in Group I and 11 days in Group II with P = 0.032. Conclusion: We have evaluated that medical expulsive therapy using tamsulosin alone is also effective and can be used in patients where steroids are contraindicated, but by adding deflazacort, it becomes very effective for management of distal ureteral calculi.
Authors and Affiliations
Alok Ranjan Sinha, Vikas Siwach
Keywords
Related Articles
- EP ID EP483701
- DOI -
- Views 122
- Downloads 0
Ligamentous Reconstruction for Post-traumatic Chronic Instability of Distal Radioulnar Joint
Introduction: Disorders of the distal radioulnar joint (DRUJ) are a common source of ulnar-sided wrist pain. The ulnar side of the wrist has often been likened to the lower back because of the difficulties involved in es...
Demographic and Clinical Profiles of Patients with Intracranial Neoplastic Mass Detected In Magnetic Resonance Imaging: A Retrospective Study
Introduction: Brain tumor account for 85% to 90% of all primary central nervous system (CNS) tumors. It is common in children and elderly. Rest account for secondary brain tumor (metastasis). It is more common in adults....
Evaluation of Functional Outcome of Anterior Cruciate Ligament Reconstruction using Bone-patellar Tendon-bone Graft
Introduction: Anterior cruciate ligament (ACL) reconstruction nowadays is probably the most common arthroscopic procedure of the knee and the choice of graft to be used for it is probably the most important decision to b...
Role of a Dental Surgeon in Management of Oral Cancer Patients: A Review Article
In the 21st century, oral cancer is rapidly becoming a global health priority. Head and neck cancer ranks among the top three cancers in India and its treatment involves radiotherapy, which has various dental complicatio...
Major Effects of Delayed Graft Function and Cold Ischemia Time on Renal Allograft Survival
Background: There is mounting evidence from experimental and clinical studies that the quality of organs from cadaver donors may be influenced by events occurring around the time of brain death, and that these may affect...