Evaluation of two ELISA IgM assays in leptospirosis outbreak research.
Journal Title: Revista Peruana de Medicina Experimental y Salud Publica - Year 2008, Vol 25, Issue 3
Abstract
Was assessed two rapid tests for serodiagnosis of acute leptospirosis, the ELISA IgM pool (Instituto Nacional de Salud, Lima), compared with a commercial ELISA IgM (PANBIO) against the gold standard microagglutination test (MAT). We examined 24 patients admitted to a hospital for investigation of a leptospirosis outbreak. It took two samples of serum, the first when they were hospitalized and the second when the consultation or discharged from the hospital. Leptospirosis were diagnosed in 19 of 24 patients by MAT. ELISA IgM pool was show a better sensitivity for acute samples that commercial IgM ELISA (73.7% vs 31.6%), positive (93.3 vs 85.7%) and negative (44.4 vs 23.5%) predictive values and same specificity (80%). In the evolution of convalescent sera had the same performance, sensitivity of 100% and specificity of 80%. The rapid test of ELISA IgM pool is highly sensitive and specific, Not requiring specialized equipment and are available for use in any laboratory.
Authors and Affiliations
Manuel Céspedes, Lourdes Balda, Martha Glenny
Keywords
Related Articles
- EP ID EP83012
- DOI -
- Views 154
- Downloads 0
Health risk to non-ionizing radiation by the electricity networks in Peru.
We review most important national and international publication, specially those which has been conducted within the framework of the International Electromagnetic Field Project of the World Health Organization, for know...
Pseudomonas aeruginosa productora de betalactamasa clásica y de espectro extendido en reservorios de un servicio de neonatología.
Para determinar la frecuencia de [i]Pseudomonas aeruginosa [/i]productoras de betalactamasa clásica (BLC) y de espectro extendido (BLEE) en reservorios del servicio de neonatología del Hospital Regional de Cajamarca, ent...
Identificación y distribución de los murciélagos vampiros del Perú
Se presenta una clave dicotómica para diferenciar los principales grupos de murciélagos presentes en el Perú, incluyendo las tres especies de murciélagos vampiros: [i]Desmodus rotundus, Diphylla ecaudata[/i] y [i]Diaemus...
Ethical considerations for conducting research in native communities of the Amazon jungle from Perú.
The progress of the medicine is had due to research development. In this scenario, and involved in the anxiety of find answers to his own questions, we find the researcher that had consciously or unconsciously trampled t...
Behavioral response of Aedes aegypti (Linnaeus, 1762) exposed to pyretrhoids insecticides of frequently use in public health
[i][b]Objectives.[/b][/i] To assess the behavioural response of the F1 generation of [i]Aedes aegyti [/i](L) collected in the Metropolitan area of Monterrey (Nuevo Leon, Mexico) vs. three adulticides pyrethroids frequent...