Evaluation of Uterine Biophysical Profile and to Assess its Role in Predicting Conception among Unexplained Primary Infertility Patients
Journal Title: Indian Journal of Community Health (IJCH) - Year 2014, Vol 26, Issue 4
Abstract
Introduction: Infertility is a devastating disease which affects its victims at a very basic level the ability to reproduce. This can be divisive to the couples involved, their relatives and friends. The influence of infertility can be immense. There are a lot of medical and social consequences of infertility and the psychological sequelae are one of them. Affected patients and their families suffer from loss of esteem, disappointment and depression. Considering the immense effect of infertility on the life of not only the affected couples but also on their families and relatives the present study was conducted with following objective. Objective: To evaluate the Uterine Biophysical Profile and to assess its role in predicting the conception outcome in spontaneous cycles in patients with unexplained primary infertility. Material &Methods: A prospective observational study was conducted in the Department of Obstetrics and Gynaecology, U.P. Rural Institute of Medical Sciences & Research, Saifaion 55 women with unexplained primary infertility after standard diagnostic work up. Ultrasound (TVS) measurement of all patients was performed in their midcycle of spontaneous cycle. The Uterine Biophysical Profile (UBP) i.e. certain sonographic qualities of the uterus were noted during the normal mid-cycle of these patients. These included 7 parameters: Endometrial thickness in greatest AP dimension of 7 mm or greater (full-thickness measurement), a layered ("5 line") appearance to the endometrium, myometrial contractions causing a wave like motion of the endometrium, homogeneous myometrial echogenicity, uterine artery blood flow (as measured by PI, less than 3.0), blood flow within zone 3 using color doppler technique, myometrial blood flow seen on gray-scale examination. The Uterine Scoring System for Reproduction ("USSR") was used to evaluate the total score. Results: Among 55 unexplained primary infertility patients 24 i.e. 43.63% conceived by serial ultrasonographic monitoring of spontaneous menstrual cycle and timed intercourse. According to USSR, with a ‘perfect score’ of 20, there was 80% conception rate. While 9 /15 patients (i.e 60%) conceived with a score of 17-19. With a score of 14-16, 10/23 patients conceived i.e. 43.37%. Only 8.33% conception rate was seen with a low score of < or = 13. Highest pregnancy rate (60%) was seen with an endometrial thickness of 7-9mm while zone IV endometrial blood flow gave maximum conception rate of 66.66%. Conclusion: UBP can prove to be a simple, reliable, reproducible, rapid and non-invasive tool to predict uterine environment and hence conception outcome.
Authors and Affiliations
Pooja Gupta, Subrat Chandra, Amit Kaushik, Pankaj Jain
Keywords
Related Articles
- EP ID EP133593
- DOI -
- Views 119
- Downloads 0
Determinants of family planning acceptance and changing social norms among the tribes of Tamil Nadu – A qualitative exploration
Background: There are very few studies done among tribes that explore the contribution of changing social norms which influences the acceptance of family planning methods. Objective: To discover various changing traditio...
Epidemiology of Road Traffic Injuries in a Tertiary Care Centre of Lucknow
Introduction: Road traffic injuries are an important cause of mortality and morbidity worldwide. It is the second leading cause of mortality in 15-29 year age group and if the current trend continues then it will be the...
Awareness and utilization of social security scheme and other government benefits by the elderly – A study in rural area of district Dehradun
Background: The rapid ageing of India’s population, has highlighted the need for better economic security arrangements for the elderly. Increased longevity is making care of the elderly more expensive and traditional fam...
Effectiveness of individual health education on the practice of dengue fever prevention in an urban area of Puducherry, India
Background: Prevention of breeding of Aedes mosquito is an effective method for dengue control. Practice of source reduction to prevent breeding depends on the knowledge of the community, which can be improved by health...
Morbidity pattern and their socio-demographic co-relates among rural primary school children in eastern Uttar Pradesh: A cross-sectional study
Research question: What is the morbidity pattern among primary school children in rural area of Varanasi and what their socio-demographic co-relates are? Objective: To study the morbidity pattern among of primary school...