EVALUATION ON LIPID PEROXIDATION AND ANTIPROLIFERATIVE ACTIVITIES OF RAPHANUS SATIVUS L
Journal Title: International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL) - Year 2016, Vol 5, Issue 6
Abstract
Raphanus sativus L. is a most commonly used vegetable belonging to the family Cruciferae. In the present study, the plant material was procured and processed for cold extraction procedure using 70% ethanol. The extract was screened for the qualitative phytochemical analysis, in vitro lipid peroxidation inhibition and antiproliferative activites. From the results, Raphanus sativus L. revealed potent lipid peroxidation inhibition with an IC50 value 281.9 µg/mL compared to standard ascorbic acid and BHT. Further, MTT assay was used to measure cell proliferation against NIH-3T3, DLA and MCF7 cell lines and the significant results were recorded in the plant extract with an IC50 value of 415.4 µg/mL, 423.2 µg/mL and 703.5 µg/mL respectively.
Authors and Affiliations
Jamuna K. S. | Molecular Biomedicine Laboratory, PG Dept. of Studies and Research in Biotechnology, Sahyadri Science College, Kuvempu University, Shimoga - 577203, Karnataka, India, Suma M. S. | Molecular Biomedicine Laboratory, PG Dept. of Studies and Research in Biotechnology, Sahyadri Science College, Kuvempu University, Shimoga - 577203, Karnataka, India, Ramesh C. K| Molecular Biomedicine Laboratory, PG Dept. of Studies and Research in Biotechnology, Sahyadri Science College, Kuvempu University, Shimoga - 577203, Karnataka, India, Riaz Mahmood| Postgraduate Department of Studies and Research in Biotechnology and Bioinformatics, Jnana Sahyadri, Kuvempu University, Shimoga 577451, Karnataka, India, Prabhakar B T| Molecular Biomedicine Laboratory, PG Dept. of Studies and Research in Biotechnology, Sahyadri Science College, Kuvempu University, Shimoga - 577203, Karnataka, India
Keywords
Related Articles
- EP ID EP15988
- DOI -
- Views 380
- Downloads 32
Potential Therapeutic use of Streblus asper: A Review
Streblus asper (Family: Moraceae) is a small tree which mainly located in India, Thailand, Malaysia and Philippines. Generally, it is usually known as Sihor (Hindi), Sheora (Bengali), Pitaphalaka (Sanskrit) and Piraaya...
INVESTIGATING THE EFFECT RELATED TO QUALITIES OF SERVICES ON THE BASIS OF SERVQUAL MODEL (SERVICE QUALITY MODEL) ON OCCUPATIONAL PERFORMANCE OF PROVIDERS OF HEALTH SERVICES OF SHAHID MOTAHARI AND PEYMANIE HOSPITALS IN JAHROM
Introduction: Hospitals are considered one of the most important units of presenting services in health system and investigating qualities of presented services are so important in them. Methodology: This study is anal...
Formulation and evaluation pf Phospholipid complex of Green Tea Polyphenol
OBJECTIVE: Phospholipid complexes are formulated to improve absorption, bioavailability and stability of herbal product. There are many herbal extracts having excellent in-vitro activity but less in-vivo activity becau...
Evaluation of anti-obesity activity of Centratherum anthelminticum in obese rats
The effect of Ethanolic extracts of Centratherum anthelminticum on adiposity index serum levels of liver enzyme in obese rats investigated. twenty mature (180-210gm body weight) Swiss albino rats either sex randomly di...
Evaluation of Synergistic Anti-microbial efficacy of plant extracts and their formulation as Topical Agents
The objective of the present study was to evaluate the antimicrobial activity of Cassia fistula, Ficusreligiosa, Milletiapinnataand Wendlandiathyrsoideaand to check the synergistic efficacy of these extracts when combi...