EXISTING EVIDENCE FOR SAFE USE OF HERBAL MEDICINES IN CHRONIC KINEY DISEASE
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 9
Abstract
There has been a widespread use of herbal medicines in the last two decades, despite a lack of scientific evidence for their efficacy and safety. Health care professionals have expressed growing concerns about safety issues relating to use herbal medicine, particularly in patients with renal or liver insufficiency. This review will propose how to use existing evidence to suggest the safe use of herbal medicines in patients with renal insufficiency, as well as transferring toxicity findings of herbal medicines from animal studies to use in humans.Safety information from postmarketing surveillance and case reports is likely to be the main information sources. However, there is little data relating to herbal medicines used by patients with chronic kidney disease. When human studies are lacking, animal studies can be seen as a substitute source of reliable information. An animal dose related to renal toxicity is used to calculate a theoretical human equivalent dose in order to estimate the toxicity in humans. However, this information should be used with caution. When herbal medicines used by people with renal insufficiency have, as yet, yielded no evidence of nephropathy, health care providers should regularly monitor kidney function of such people, together with their electrolytes. Observational studies are required to examine the renal adverse effects of herbal medicines.Â
Authors and Affiliations
Mayuree Tangkiatkumjai
Keywords
Related Articles
- EP ID EP578400
- DOI -
- Views 72
- Downloads 0
BACTERIOCIN: A NOVEL APPROACH FOR PRESERVATION OF FOOD
Bacteriocins are antimicrobial peptides which are ribosomally synthesized and produced by Lactic acid bacteria. They play a major role in prevention of human disease such as cancer, inflammatory disease, respiratory in...
SOLID DISPERSION TECHNIQUE TO ENHANCE THE SOLUBILITY AND DISSOLUTION RATE OF ARIPIPRAZOLE BY FUSION METHOD
Objective: The objective of the present study was to enhance the solubility and dissolution rate of Aripiprazole (APZ), a water insoluble drug, by a solid dispersion technique.Methods: Solid dispersions (SD) of APZ were...
ANTIBACTERIAL ACTIVITY OF SELECTED MEDICINAL PLANT IN TRADITIONAL TREATMENT OF WOUND INFECTION IN SOUTHEAST INDIA
Objective: The wound healing potential of fruit peel of Pithecellobium dulce Benth, a plant traditionally used for wound treatment against wound- infecting bacteria, was assessed using disc diffusion and microtitre plate...
ANTIFUNGAL ACTIVITY OF CYANOTIS AXILLARIS (L.) D. DON EX SWEET AGAINST OPPORTUNISTIC FUNGAL STRAINS
Objective: The main focus of the study was to compare and determine the antifungal activities of different solvent extracts of Cyanotis axillaris.Methods: The dried whole plant of C. axillaris was extracted by sequential...
AN IMPROVED RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ASPIRIN, ATORVASTATIN, AND CLOPIDOGREL IN PHARMACEUTICAL FORMULATION USING EXPERIMENTAL DESIGN METHODOLOGY
Objective: In this study an improved RP-HPLC method was developed for the simultaneous estimation of Aspirin, Atrovastatin, and Clopidogrel in pharmaceutical dosage form. For improving the separation, an experimental des...