Extraction Of Methicillin Resistant Staphylococcus Aureus (Mrsa) Golden Pigment And Study It Antioxidant Activity On Macrophage Killing Pathway
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 4
Abstract
Staphylococcus aureus isolate was obtained from microbiology lab of biology department and reidentified as methicillin resistance Staphylococcus aureus (MRSA) by biochemical test and methicillin kit. Staphyloxanthin pigment was extracted by ethanol and centrifugation method. Effect of antioxidant activity of this pigment was studied on macrophage cell by using blood specimen and DPA. The result were showed the MRSA cell which treated with DPA and mixed with blood give no bacterial growth, while MRSA cell without treatment with DPA give bacterial growth. This means the DPA inhibit pigment synthesis and no antioxidant for macrophage happened and engulfment of bacterial cell happened and shows no growth for bacteria.
Authors and Affiliations
Rasmiya Abed Aburesha, Hind Hussein, Zainab Zamel Khalaf, Ban Jasim Mohamed
Keywords
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- EP ID EP395646
- DOI 10.9790/3008-1304054043
- Views 78
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