Extramedullary Hematopoiesis in a Patient with Transfusion Dependent Beta-Thalassemia Presenting with Cord Compression
Journal Title: Iranian Journal of Blood and Cancer - Year 2018, Vol 10, Issue 1
Abstract
Extramedullary hematopoiesis (EMH) is a physiological compensatory phenomenon occurring in many hemolytic anemias including thalassemia. Besides transfusion, radiotherapy, surgery or a combination of these modalities, hydroxyurea (HU) as an optimal treatment has been described occasionally. We described a case of beta-thalassemia major who has been on regular blood transfusion and developed EMH that was treated with HU combined with radiotherapy. EMH should also be considered in thalassemia major patients, although it is more common in non-transfusion dependent thalassemia patients. HU combined with low dose radiotherapy along with regular blood transfusion are suggested as good treatment options for patients with EMH.
Authors and Affiliations
Mehran Karimi, Tahereh Zarei, Parisa Pishdad
Keywords
Related Articles
- EP ID EP358752
- DOI -
- Views 106
- Downloads 0
Hemorrhage Treatment Report of Patients Suffering from Glanzmann’s Thrombasthenia Resulting Hospitalization from 2006 to 2011 at Mofid Children’s Hospital
Background: The present study evaluated treatment outcomes and the treatment indexes among Glanzmann’s patients in Mofid Children’s Hospital, Tehran, Iran. Patients and Methods: A retrospective cross-sectional study was...
Recurrent Cytomegalovirus Retinitis in a Patient with Leukemia on Maintenance Chemotherapy
This article has no abstract.
Pulmonary Capillary Leak Syndrome
This article has no abstract.
Features of Bone Sarcomas at MAHAK Children Hospital, Tehran, Iran during 2007-2009
Background: Bone sarcomas are the most common malignancies of bone tissues in children, and are classified into two groups as osteosarcoma and Ewing’s Sarcoma. Treatment and prognosis depend on the subtype and grade of t...
Transfusion-Transmitted Viruses in Individuals with β Thalassemia Major at Northeastern Iran, a Retrospective Sero-Epidemiological Survey
Background: Thalassemia syndromes are the most common genetic disorders in the world. They happen due to genetic defects in process of haemoglobin synthesis, and would be classified to many groups mainly α and β, based o...