FABRICATION OF SILVER NANOPARTICLES SYNTHESIZED FROM GANODERMA LUCIDUM INTO THE COTTON FABRIC AND ITS ANTIMICROBIAL PROPERTY
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 8
Abstract
Objectives: To synthesize and characterize the silver nanoparticles from the mushroom, Ganoderma lucidum and application of this nanoparicle into the cotton fabric to impart sterility.Methods: SNPs synthesised by using the fruiting body of Ganoderma lucidum, Resulted AgNPs fabricated cotton fabric was characterized using SEM (Scanning Electron Microscope) and silver nanoparticles produced from G. lucidum were characterized using UV-VIS Spectrophotometer, SEM, FE-SEM (Field Emission Scanning Electron Microscope), EDAX (Energy dispersion X-RAY spectroscopy)and XRD (X-ray diffraction spectroscpy). Then the incorporated cotton fabric was tested against 5 different strains.Results: The results showed that cotton fabric incorporated with AgNPs displayed significant antibacterial activity against all the selected strains.Conclusion: It was demonstrated that application of biologically synthesized AgNPs production and fabrication of cotton fabric, indicates sterile properties. Further it can be modified as perfect wound dressing material in the health care market. Moreover to avoid the damage to the environment the fabric containing silver nanoparticles can be treated with cyanogenic bacterial strains.
Authors and Affiliations
Sneha Paul, Changam Sheela Sasikumar, Anita Rj Singh
DEVELOPMENT AND VALIDATION OF A STABILITY-INDICATING ISOCRATIC REVERSE PHASE-LIQUID CHROMATOGRAPHY ASSAY FOR DETERMINATION OF PHENYTOIN IN BULK AND PHARMACEUTICAL FORMULATIONS
Objective: To develop and validate a stability-indicating reversed phase high performance liquid chromatography (RP-HPLC) assay for the determination of phenytoin in bulk and pharmaceutical dosage forms.Methods: A HPLC i...
DEVELOPMENT AND VALIDATION OF HPLC/UV METHOD FOR DETERMINATION OF MELOXICAM IN HUMAN PLASMA AND APPLICATION IN PHARMACOKINETIC STUDIES
Objective: To develop and validate a modified isocratic reversed-phase high performance liquid chromatographic/ultraviolet (RP-HPLC/UV) method for determination of Meloxicam in human plasma to be used for pharmacokinetic...
DOCKING AND CYTOTOXICITY STUDIES OF 2-VINYLCHROMONE DERIVATIVES ON HUMAN BREAST CANCER CELL LINES
Objective: Estrogen receptor (ER) is over-expressed in 70% of breast cancers. The ER has two isoforms, ERα and ERβ. The ER ligand binding domain (LBD) has been the target for hormone-responsive breast cancer. Due to ti...
RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF GATIFLOXACIN AND AMBROXOL HCL IN PHARMACEUTICAL DOSAGE FORM
Objective: To develop a simple, selective, linear, precise and accurate RP-HPLC method for simultaneous estimation of Gatifloxacin and Ambroxol HCl in tablet dosage form.Methods: The chromatographic separation was perfor...
DRUG UTILIZATION EVALUATION OF ANTIBIOTICS IN GENERAL MEDICINE DEPARTMENT OF A TERTIARY CARE HOSPITAL
Objective: Conventional need of broad spectrum antibiotics for multiple organ infections in hospital, ensue the problem of resistance. Most of the antibiotic utilization is empirical leading to their irrational prescript...