FACTORS ASSOCIATED WITH OUTCOMES OF DRUGRESISTANT TUBERCULOSIS
Journal Title: Pulmonologija ir alergologija - Year 2017, Vol 1, Issue 2
Abstract
Objective. To determine factors associated with treatment outcomes among DR-TB (drug-resistant tuberculosis). Methodology. The study included 64 patients who were treated for pulmonary DR-TB in the hospital of Lithuanian University of Health Sciences (LUHS) Kauno klinikos Pulmonology Department and affiliated hospital Romaniai Hospital of Tuberculosis in 2014. The retrospective analysis of patients’ case-histories was conducted. The most common outcomes and their association with various factors were evaluated. Statistical data analysis was performed using SPSS 20.0; Chi square test was performed. The differences were identified as statistically significant when p<0.05. Results. 54.7% of all treatment outcomes were unsuccessful. Following the data analysis it was observed that factors which can be associated with death are disseminated TB and outspread of TB in all 5 lobes. Alcohol consumption and older age were associated with death and treatment default. Treatment success could be associated with younger age, no consumption of alcohol, infiltrative TB and acid-fast bacilli smear negativity at the start of the treatment. In all cases p<0.05. Conclusions. Alcohol consumption and advanced TB forms are the corrected factors for unsuccessful outcomes. To reach better results, the access to early diagnostics of TB should be improved as well as the control of alcohol consumption.
Authors and Affiliations
Ieva Gaudiešiūtė, Greta Musteikienė, Skaidrius Miliauskas
Keywords
Related Articles
- EP ID EP262835
- DOI -
- Views 110
- Downloads 0
FIBROBRONCHOSCOPY IN THE DIAGNOSIS OF LUNG DISEASES
Flexible bronchoscopy is an endoscopic method, which visually identified abnormalities within the airway, mucosa of trachea and bronchi. Since the 1970s, flexible bronchoscopy has begun to be w...
Eosinophil induced airway smooth muscle remodelling in asthma
Characteristics of the studied subjects: A total of 39 nonsmoking adults participated in the study (22 steroid-free patients with intermittent or mild-to moderate persistent asthma, and 17 healthy participants who consti...
LUNG CANCER IMMUNOTHERAPY
The immune system plays a crucial role in protecting the body against cancer by recognizing and destroying cells it perceives as foreign. Cancer immunity strategies aim to restore immunity sy...
INHALED TRIPLE THERAPY IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: TRIBUTE CLINICAL STUDY DATA
Chronic obstructive pulmonary disease (COPD) is characterised by persistent respiratory symptoms and airflow limitation. Due to disease severity, exacerbations, exacerbations, affecting the quality of life,...
MECHANOBIOLOGY IN STRUCTURAL LUNG CELLS AND THE IMPORTANCE OF IT’S CHANGES IN ASTHMA
Mechanobiology is an emerging field of science at the interface of biology and engineering that focuses on how physical forces and changes in the mechanical properties of cells and tissues contribute to development, cell...