Fetal Left Ventricle Modified Myocardial Performance Index: Defining Normal Values in the Third Trimester in Rural Central India
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 11
Abstract
Introduction: Myocardial performance index (MPI) is an emerging non-invasive parameter for in utero monitoring of fetal well-being. Purpose: The aim of this study was to determine normal values for fetal left ventricle (LV) modified MPI (Mod-MPI) in Indian population and to assess its relation to advancing gestation and fetal heart rate (FHR). Materials and Methods: In this study, 60 normal pregnant women were included whose fetuses were having structurally normal hearts. Fetal echocardiography was done to measure the LV Mod-MPI. MPI was calculated after measuring various time intervals including isovolumetric contraction time (ICT), isovolumetric relaxation time (IRT), and ejection time (ET), and the formula used for MPI calculation was ICT + IRT/ET. Further, linear regression analysis was done to find a correlation of MPI with the gestation age and FHR. Results: The normal MPI in the third-trimester fetuses of the Indian population was 0.35 ± 0.03. The mean ICT was 31.40 ± 2.95 ms, mean IRT was 32.38 ± 3.42 ms, and mean ET was 174.83 ± 6.41 ms. The mean heart rate was 142 ± 6 bpm. The LV Mod-MPI was not significantly associated with either FHR or advancing gestation. Conclusion: Fetal global cardiac function can be assessed by MPI. FHR, ventricular size, and geometry or image quality do not have any effect on MPI. MPI has a significantly important role in the monitoring of complicated pregnancies.
Authors and Affiliations
Atul T Tayade, Sonia Singh, Saurabh Patil
Keywords
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