Fibrates for Primary Biliary Cholangitis: What’s All the Hype?
Journal Title: Annals of Hepatology - Year 2017, Vol 16, Issue 5
Abstract
Ursodeoxycholic acid is the first-line therapy for primary biliary cholangitis. However, a subset of patients fail to show biochemical response. For these patients, adjuvant therapies are warranted. Obeticholic acid was conditionally approved as a second-line drug. Evidence is building up in favor of fibrates, which are available for off-label use.
Authors and Affiliations
Cynthia Levy
Keywords
Related Articles
- EP ID EP208866
- DOI 10.5604/01.3001.0010.2709
- Views 103
- Downloads 0
Prevalence and resistance pattern of genotype G and H in chronic hepatitis B and HIV co-infected patients in Mexico
Objective. We estimated the prevalence and identified the resistance pattern of HBV genotypes H and G in HBV monoinfected and HIV co-infected patients. Material and methods. A cross-sectional prevalence and analytic stud...
Impact of Fibroscan® on management of chronic viral hepatitis in clinical practice
Background. Liver stiffness measurement (LSM) using Fibroscan® is an increasingly popular non-invasive method for quantifying liver fibrosis in patients with chronic viral hepatitis. We aimed to explore potential impact...
Hepatic hemodynamics and transient elastography in alcoholic foamy degeneration: report of 2 cases
Alcoholic liver disease (ALD) covers a wide spectrum of pathology ranging from fatty liver disease to acute steatohepatitis to cirrhosis and/or hepatocellular carcinoma. Alcoholic foamy degeneration (AFD) is an uncommon,...
High frequencies of CD158b+ NK cells are associated with persistent hepatitis C virus infections
Background. During the early phases of a hepatitis C virus (HCV) infection, NK cell activation appears to be critical to the induction of adaptive immune responses that have the potential of clearing the infection. This...
Focal nodular hyperplasia vs. hemangioma:Computed tomography and magnetic resonance imaging findings
Focal nodular hyperplasia (FNH) and hemangioma are benign and generally asymptomatic hepatic tumors. With distinctive imaging findings on dynamic computed tomography (CT) and magnetic resonance imaging (MRI), differentia...